NP_001243.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
21,118 Da
NCBI Official Full Name
CD70 antigen
NCBI Official Synonym Full Names
CD70 molecule
NCBI Protein Information
CD70 antigen; CD27-L; CD27 ligand; Ki-24 antigen; surface antigen CD70; tumor necrosis factor ligand superfamily member 7; tumor necrosis factor (ligand) superfamily, member 7
UniProt Protein Name
CD70 antigen
UniProt Synonym Protein Names
CD27 ligand; CD27-L; Tumor necrosis factor ligand superfamily member 7; CD_antigen: CD70
UniProt Synonym Gene Names
UniProt Entry Name
CD70_HUMAN
NCBI Summary for CD70
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008]
UniProt Comments for CD70
CD70: Cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. Belongs to the tumor necrosis factor family.
Protein type: Membrane protein, integral; Cytokine
Chromosomal Location of Human Ortholog: 19p13
Cellular Component: extracellular space; integral to plasma membrane; plasma membrane
Molecular Function: protein binding; protease binding; cytokine activity; tumor necrosis factor receptor binding; receptor binding
Biological Process: cell proliferation; cell-cell signaling; immune response; signal transduction
Research Articles on CD70
Precautions
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Products associated with CD70 elisa kit
Pathways associated with CD70 elisa kit
Diseases associated with CD70 elisa kit
Organs/Tissues associated with CD70 elisa kit
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