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anti-14-3-3 alpha/beta antibody :: Mouse 14-3-3 alpha/beta Monoclonal Antibody

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Catalog # MBS838572
Unit / Price
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  0.1 mg  /  $395 +1 FREE 8GB USB
Western Blot (WB)
Product Name

14-3-3 alpha/beta, Monoclonal Antibody

Full Product Name

14-3-3 alpha/beta antibody

Product Synonym Names
Monoclonal 14-3-3 alpha/beta; Anti-14-3-3 alpha/beta; KCIP-1; KCIP1; YWHAB; HS1; GW128; YWHAA; KCIP 1; 14-3-3 alpha+beta; 14-3-3 alpha beta
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Supplied in citrate-tris-HCl buffer, pH 7.0 with 0.02% Proclin 300
1 mg/ml (lot specific)
Biological Significance
14-3-3 alpha/beta prevents apoptosis by sequestering Bad to the cytosol.
14-3-3 alpha/beta antibody was raised in Mouse using a synthetic peptide (KLH-coupled) corresponding to near C-terminal residues of 14-3-3b/a protein as the immunogen
Preparation and Storage
Aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze/thaw cycles
Other Notes
Small volumes of anti-14-3-3 alpha/beta antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-14-3-3 alpha/beta antibody
Mouse monoclonal 14-3-3 alpha/beta antibody
Applications Tested/Suitable for anti-14-3-3 alpha/beta antibody
Western Blot (WB)
Application Notes for anti-14-3-3 alpha/beta antibody
WB: 1:1000-1:2000

Western Blot (WB) of anti-14-3-3 alpha/beta antibody
Western blot analysis on mouse liver lysates using anti-14-3-3 b/a monoclonal antibody.
anti-14-3-3 alpha/beta antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for 14-3-3 alpha/beta. It may not necessarily be applicable to this product.
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
27,850 Da
NCBI Official Full Name
14-3-3 protein beta/alpha
NCBI Official Synonym Full Names
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
NCBI Official Symbol
YWHAB  [Similar Products]
NCBI Official Synonym Symbols
HS1; GW128; YWHAA; KCIP-1; HEL-S-1
  [Similar Products]
NCBI Protein Information
14-3-3 protein beta/alpha
UniProt Protein Name
14-3-3 protein beta/alpha
UniProt Synonym Protein Names
Protein 1054; Protein kinase C inhibitor protein 1; KCIP-1
UniProt Gene Name
YWHAB  [Similar Products]
UniProt Synonym Gene Names
KCIP-1  [Similar Products]
UniProt Entry Name
NCBI Summary for 14-3-3 alpha/beta
This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for 14-3-3 alpha/beta
14-3-3 beta: a protein of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. A multifunctional regulator of the cell signaling processes.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 20q13.1

Cellular Component: focal adhesion; cytoplasmic vesicle membrane; transcriptional repressor complex; membrane; perinuclear region of cytoplasm; cytoplasm; melanosome; cytosol; nucleus

Molecular Function: protein C-terminus binding; protein domain specific binding; protein binding; enzyme binding; histone deacetylase binding; protein complex binding; phosphoprotein binding; transcription corepressor activity; phosphoserine binding

Biological Process: epidermal growth factor receptor signaling pathway; positive regulation of catalytic activity; negative regulation of protein amino acid dephosphorylation; axon guidance; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; activation of MAPKK activity; apoptosis; protein heterooligomerization; MAPKKK cascade; small GTPase mediated signal transduction; Ras protein signal transduction; cytoplasmic sequestering of protein; insulin receptor signaling pathway; innate immune response; gene expression; vascular endothelial growth factor receptor signaling pathway; negative regulation of transcription, DNA-dependent; protein targeting
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