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anti-ACTG1 antibody :: Mouse ACTIN F TYPE Monoclonal Antibody

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Catalog # MBS212994
Unit / Price
  0.5 mg  /  $420 +1 FREE 8GB USB
anti-ACTG1 antibody
Product Name

ACTIN F TYPE (ACTG1), Monoclonal Antibody

Full Product Name

MOUSE ANTI HUMAN F-ACTIN

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
102560
Clonality
Monoclonal
Isotype
IgM
Clone Number
NH3
Host
Mouse
Form/Format
Purified
Purified IgM - liquid
Concentration
IgM concentration 1.0 mg/ml (lot specific)
Perservative Stabilisers
0.09% Sodium Azide
Preparation
Immunogen
Human monocytes and U937 cell line
Fusion Partners
Target Species
Human
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Other Notes
Small volumes of anti-ACTG1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ACTG1 antibody
Mouse anti Human F-Actin antibody, clone NH3 recognizes human Filamentous actin (F-actin). The antibody binds to the N-terminal region of actin, but not to the extreme N-terminal 40 amino acids. In tissue sections the antibody stains the cytoplasm of macrophages strongly, and gives granular, localised nuclear staining of all cell types.
Applications Tested/Suitable for anti-ACTG1 antibody
Immunohistology Frozen, ELISA (EIA), Flow cytometry (FC/FACS), Western Blot (WB)
Application Notes for anti-ACTG1 antibody
ELISA: Maximum Dilution: 1 / 10;
Flow Cytometry: Maximum Dilution: 1 / 10;
Western Blotting: Minimum Dilution: 1/100; Maximum Dilution: 1/500
NCBI/Uniprot data below describe general gene information for ACTG1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
41,793 Da[Similar Products]
NCBI Official Full Name
actin, cytoplasmic 2
NCBI Official Synonym Full Names
actin gamma 1
NCBI Official Symbol
ACTG1  [Similar Products]
NCBI Official Synonym Symbols
ACT; ACTG; BRWS2; DFNA20; DFNA26; HEL-176
  [Similar Products]
NCBI Protein Information
actin, cytoplasmic 2; cytoskeletal gamma-actin; epididymis luminal protein 176
UniProt Protein Name
Actin, cytoplasmic 2
UniProt Synonym Protein Names
Gamma-actinActin, cytoplasmic 2, N-terminally processed
Protein Family
UniProt Gene Name
ACTG1  [Similar Products]
UniProt Synonym Gene Names
UniProt Entry Name
ACTG_HUMAN
NCBI Summary for ACTG1
Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, gamma 1, encoded by this gene, is a cytoplasmic actin found in non-muscle cells. Mutations in this gene are associated with DFNA20/26, a subtype of autosomal dominant non-syndromic sensorineural progressive hearing loss. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2011]
UniProt Comments for ACTG1
ACTG1: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Belongs to the actin family.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 17q25

Cellular Component: filamentous actin; extracellular space; cytoskeleton; myofibril; membrane; plasma membrane; nucleus; cytosol

Molecular Function: identical protein binding; protein binding; structural constituent of cytoskeleton; ubiquitin protein ligase binding; ATP binding

Biological Process: retinal homeostasis; intercellular junction assembly and maintenance; axon guidance; ephrin receptor signaling pathway; innate immune response; sarcomere organization; cell motility; vascular endothelial growth factor receptor signaling pathway

Disease: Baraitser-winter Syndrome 2; Deafness, Autosomal Dominant 20
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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