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anti-ACOT11 antibody :: Mouse Acyl-Coenzyme A Thioesterase 11 Monoclonal Antibody

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Catalog # MBS140211
Unit / Price
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  0.005 mg  /  $140 +1 FREE 8GB USB
  0.02 mg  /  $205 +1 FREE 8GB USB
  0.1 mg  /  $505 +1 FREE 8GB USB
anti-ACOT11 antibody
Product Name

Acyl-Coenzyme A Thioesterase 11 (ACOT11), Monoclonal Antibody

Full Product Name

Mouse Anti Human Acyl-Coenzyme A Thioesterase 11

Product Synonym Names
ACOT11 Antibody; Acyl-Coenzyme A Thioesterase 11, Mouse Anti Human; Acyl-coenzyme A thioesterase 11; Acyl-CoA thioesterase 11; Acyl-CoA thioester hydrolase 11; Brown fat-inducible thioesterase; BFIT; Adipose-associated thioesterase; ACOT11; BFIT; KIAA0707; THEA; BFIT1; BFIT2; THEM1; STARD14
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
606803
Clonality
Monoclonal
Isotype
IgG2b heavy chain and kappa light chain
Clone Number
PJ4B2AT
Host
Mouse
Purity/Purification
ACOT11 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Form/Format
1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
Immunogen
Anti-human ACOT11 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human ACOT11 amino acids 19-250 purified from E Coli.
Preparation and Storage
For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles.
12 months at -20 degree C. 1 month at 4 degree C.
Other Notes
Small volumes of anti-ACOT11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ACOT11 antibody
Introduction: ACOT11 is a protein with acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. Expression of a similar murine protein in brown adipose tissue is induced by cold exposure and repressed by warmth. Expression of the mouse ACOT11 has been linked to obesity, with higher expression found in obesity-resistant mice compared with obesity-prone mice.
Applications Tested/Suitable for anti-ACOT11 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-ACOT11 antibody
ACOT11 antibody has been tested by ELISA, Western blot and immunohistochemistry analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot is 1:500 ~ 1:2,000 and immunohistochemistry analysis is 1:50~100. Recommended starting dilution for Western blot is 1:1,000 and Immunohistochemistry is 1:100.
NCBI/Uniprot data below describe general gene information for ACOT11. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
67,152 Da
NCBI Official Full Name
acyl-coenzyme A thioesterase 11 isoform 1
NCBI Official Synonym Full Names
acyl-CoA thioesterase 11
NCBI Official Symbol
ACOT11  [Similar Products]
NCBI Official Synonym Symbols
BFIT; THEA; THEM1; STARD14
  [Similar Products]
NCBI Protein Information
acyl-coenzyme A thioesterase 11; START domain containing 14; StAR-related lipid transfer (START) domain containing 14; acyl-CoA thioester hydrolase 11; adipose-associated thioesterase; brown fat-inducible thioesterase; thioesterase superfamily member 1; thioesterase, adipose associated
UniProt Protein Name
Acyl-coenzyme A thioesterase 11
UniProt Synonym Protein Names
Acyl-CoA thioester hydrolase 11; Adipose-associated thioesterase; Brown fat-inducible thioesterase; BFIT
UniProt Gene Name
ACOT11  [Similar Products]
UniProt Synonym Gene Names
BFIT; KIAA0707; THEA; Acyl-CoA thioesterase 11; BFIT  [Similar Products]
UniProt Entry Name
ACO11_HUMAN
NCBI Summary for ACOT11
This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]
UniProt Comments for ACOT11
ACOT11: Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Hydrolase; EC 3.1.2.-

Chromosomal Location of Human Ortholog: 1p32.3

Cellular Component: cytoplasm

Molecular Function: acyl-CoA hydrolase activity; lipid binding

Biological Process: response to temperature stimulus; response to cold; fatty acid metabolic process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with anti-ACOT11 antibody
 Organ/Tissue Name  Pubmed Publications
 Adipose Tissue Antibodies  >4 publications with ACOT11 and Adipose Tissue
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