NP_005849.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
NCBI Official Full Name
A-kinase anchor protein 8
NCBI Official Synonym Full Names
A kinase (PRKA) anchor protein 8
NCBI Official Synonym Symbols
AKAP-8; AKAP95; AKAP 95; AKAP-95; DKFZp586B1222 [Similar Products]
NCBI Protein Information
A-kinase anchor protein 8; A-kinase anchor protein, 95kDa
UniProt Protein Name
A-kinase anchor protein 8
UniProt Synonym Protein Names
A-kinase anchor protein 95 kDa
UniProt Synonym Gene Names
UniProt Entry Name
AKAP8_HUMAN
NCBI Summary for AKAP8
This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins are scaffold proteins that contain a binding domain for the RI/RII subunit of protein kinase A (PKA) and recruit PKA and other signaling molecules to specific subcellular locations. This gene encodes a nuclear A-kinase anchor protein that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin. A pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq]
UniProt Comments for AKAP8
AKAP8: Anchoring protein that mediates the subcellular compartmentation of cAMP-dependent protein kinase (PKA type II). Belongs to the AKAP95 family.
Protein type: RNA-binding; Adaptor/scaffold; Mitochondrial; Cell cycle regulation
Chromosomal Location of Human Ortholog: 19p13.1
Cellular Component: nucleoplasm; Golgi apparatus; nuclear matrix; membrane; mitochondrion; female pronucleus; condensed chromosome; nucleus
Molecular Function: zinc ion binding; double-stranded DNA binding
Biological Process: mitosis; mitotic chromosome condensation; signal transduction
Research Articles on AKAP8
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Products associated with anti-AKAP8 antibody
Pathways associated with anti-AKAP8 antibody
Diseases associated with anti-AKAP8 antibody
Organs/Tissues associated with anti-AKAP8 antibody
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