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anti-B2m antibody :: Mouse BETA 2 MICROGLOBULIN Monoclonal Antibody

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Catalog # MBS212291
Unit / Price
  0.1 mg  /  $190 +1 FREE 8GB USB
anti-B2m antibody
Product Name

BETA 2 MICROGLOBULIN (B2m), Monoclonal Antibody

Popular Item
Full Product Name

MOUSE ANTI RAT BETA 2 MICROGLOBULIN

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P07151
Clonality
Monoclonal
Isotype
IgG1
Clone Number
TLD-3H12B
Host
Mouse
Form/Format
Purified
Purified IgG - liquid
Concentration
IgG concentration 1.0 mg/ml (lot specific)
Perservative Stabilisers
0.09% Sodium Azide
Preparation
Immunogen
Rat microglial cells
Fusion Partners
Target Species
Rat
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Other Notes
Small volumes of anti-B2m antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-B2m antibody
Mouse anti Rat beta 2 Microglobulin antibody, clone TLD-3H12B recognizes native beta 2 microglobulin which is a component of MHC class I molecules, which are present on all nucleated cells. Levels of beta 2 microglobulin can be used to assess renal function in kidney transplant recipients. Also known as B2M, it has been suggested that this protein can be used as a prognostic marker for HIV infection.
Applications Tested/Suitable for anti-B2m antibody
Immunohistology Frozen, Flow cytometry (FC/FACS)
Application Notes for anti-B2m antibody
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul.
Flow Cytometry: Minimum Dilution: 1/10; Maximum Dilution: 1/20
NCBI/Uniprot data below describe general gene information for B2m. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
13,720 Da[Similar Products]
NCBI Official Full Name
beta-2-microglobulin
NCBI Official Synonym Full Names
beta-2 microglobulin
NCBI Official Symbol
NCBI Protein Information
beta-2-microglobulin; beta-2-microglobulin C-terminal fragment (55 AA)
UniProt Protein Name
Beta-2-microglobulin
Protein Family
UniProt Gene Name
UniProt Entry Name
B2MG_RAT
NCBI Summary for B2m
mouse homolog plays a role in the assembly and surface expression of MHC class I molecules [RGD, Feb 2006]
UniProt Comments for B2m
B2M: Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Heterodimer of an alpha chain and a beta chain. Beta-2- microglobulin is the beta-chain of major histocompatibility complex class I molecules. Polymers of beta 2-microglobulin can be found in tissues from patients on long-term hemodialysis. Belongs to the beta-2-microglobulin family.

Protein type: Secreted, signal peptide; Secreted

Cellular Component: Golgi apparatus; extracellular space; focal adhesion; membrane; cytoplasm; plasma membrane; MHC class I protein complex; external side of plasma membrane

Molecular Function: identical protein binding

Biological Process: response to drug; retinal homeostasis; iron ion homeostasis; antigen processing and presentation of peptide antigen via MHC class I; response to cadmium ion; positive regulation of T cell mediated cytotoxicity; response to molecule of bacterial origin; T cell differentiation in the thymus; protein refolding; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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