• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-CA125 antibody :: Mouse CA125 Monoclonal Antibody

Scan QR to view Datasheet
Catalog # MBS211491
Unit / Price DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.
Product Name

CA125, Monoclonal Antibody

Popular Item
Also Known As

MOUSE ANTI HUMAN CA125

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
14507
OMIM
606154
3D Structure
ModBase 3D Structure for Q8WXI7
Clonality
Monoclonal
Isotype
IgG1
Clone Number
X75 (3C8/4)
Host
Mouse
Form/Format
Purified
Purified IgG - liquid
Concentration
IgG concentration 1.0 mg/ml (lot specific)
Perservative Stabilisers
0.09% Sodium Azide (NaN3)
Preparation
Immunogen
Native CA-125 (Mucin-16).
Buffer Solution
Target Species
Human
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Other Notes
Small volumes of anti-CA125 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CA125 antibody
Mouse anti Human CA125 antibody, clone X75 (3C8/4) recognizes ovarian cancer antigen CA-125, also known as Mucin-16. Clone X75 recognizes epitope specificity group B (ISOBM classification) similar to M-11. CA-125 is a serum marker, overexpressed in epithelial ovarian cancer cells and is routinely used for patient monitoring. CA-125 was originally identified by Bast et al. using a monoclonal antibody developed against the ovarian cancer cell line OVCA433 (Bast et al. 1981). Mouse anti Human CA125 antibody, clone X75 has been sucessfully used as both a capture reagent and a detection reagent for the development of sensitive ELISA assays for the measurement of CA125 in human plasma samples.
Applications Tested/Suitable for anti-CA125 antibody
ELISA (EIA), Western Blot (WB)

Testing Data of anti-CA125 antibody
Sandwich ELISA analysis of human CA-125 expression using Mouse anti Human CA-125 antibody, clone X75 as a capture reagent and biotinylated Mouse anti Human CA-125 antibody, clone X325 (MBS214596) as a detection reagent with purified human CA-125 as antigen to generate the standard curve. Detection is by HRP conjugated streptavidin and substrate. Microtitre plate is read at O.D. 450 nm on the iMark Microplate Absorbance Reader . Plasma (green) sample at 1:2 is shown
anti-CA125 antibody Testing Data image
Testing Data of anti-CA125 antibody
Sandwich ELISA analysis of human CA-125 expression using Mouse anti Human CA-125 antibody, clone X325 (MBS214596) as a capture reagent and biotinylated Mouse anti Human CA-125 antibody, clone X75 as a detection reagent with purified human CA-125 as antigen to generate the standard curve. Detection is by HRP conjugated streptavidin and substrate. Microtitre plate is read at O.D. 450 nm on the iMark Microplate Absorbance Reader . Plasma (green) sample at 1:2 is shown
anti-CA125 antibody Testing Data image
NCBI/Uniprot data below describe general gene information for CA125. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
2,353,428 Da
NCBI Official Full Name
mucin-16
NCBI Official Synonym Full Names
mucin 16, cell surface associated
NCBI Official Symbol
MUC16  [Similar Products]
NCBI Official Synonym Symbols
CA125
  [Similar Products]
NCBI Protein Information
mucin-16; CA125 ovarian cancer antigen; ovarian cancer-related tumor marker CA125; ovarian carcinoma antigen CA125
UniProt Protein Name
Mucin-16
UniProt Synonym Protein Names
Ovarian cancer-related tumor marker CA125; CA-125; Ovarian carcinoma antigen CA125
UniProt Gene Name
MUC16  [Similar Products]
UniProt Synonym Gene Names
CA125; MUC-16; CA-125  [Similar Products]
UniProt Entry Name
MUC16_HUMAN
UniProt Comments for CA125
MUC16: Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.

Protein type: Membrane protein, peripheral; Membrane protein, integral; Cell adhesion

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: extracellular space; extrinsic to membrane; Golgi lumen; plasma membrane; integral to membrane; vesicle

Molecular Function: protein binding

Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; O-glycan processing; cell adhesion; post-translational protein modification
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000