• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-CBX5 antibody :: Mouse CBX5 Monoclonal Antibody

Scan QR to view Datasheet
Catalog # MBS8528407
Unit / Price
  0.1 mL  /  $290 +1 FREE 8GB USB
anti-CBX5 antibody
Product Name

CBX5, Monoclonal Antibody

Also Known As

Mouse Monoclonal Antibody to CBX5

Product Synonym Names
HP1; HP1A; HEL25
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
191
OMIM
604478
3D Structure
ModBase 3D Structure for P45973
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2H4E9
Host
Mouse
Immunogen
Full (1-191)
Other Notes
Small volumes of anti-CBX5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-CBX5 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
Application Notes for anti-CBX5 antibody
Western blot using Recombinant protein
Western blot using Transfection expressed protein
Western blot using Cell lysate
NCBI/Uniprot data below describe general gene information for CBX5. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
22.2kDa
NCBI Official Full Name
chromobox protein homolog 5
NCBI Official Synonym Full Names
chromobox 5
NCBI Official Symbol
NCBI Official Synonym Symbols
HP1; HP1A; HEL25
  [Similar Products]
NCBI Protein Information
chromobox protein homolog 5
UniProt Protein Name
Chromobox protein homolog 5
UniProt Synonym Protein Names
Antigen p25; Heterochromatin protein 1 homolog alpha; HP1 alpha
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
HP1A; HP1 alpha  [Similar Products]
NCBI Summary for CBX5
This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
UniProt Comments for CBX5
Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000