• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-CD2 antibody :: Mouse CD2 Monoclonal Antibody

Scan QR to view Datasheet
Catalog # MBS210313
Unit / Price
  0.1 mg  /  $410 +1 FREE 8GB USB
Product Name

CD2, Monoclonal Antibody

Popular Item
Also Known As

MOUSE ANTI HUMAN CD2:Biotin

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
351
OMIM
186990
3D Structure
ModBase 3D Structure for P06729
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
LT2
Host
Mouse
Form/Format
Biotin
Purified IgG conjugated to biotin - liquid.
Concentration
IgG concentration 0.1 mg/ml (lot specific)
Perservative Stabilisers
0.09% Sodium Azide
1% Bovine Serum Albumin
Preparation
Immunogen
Normal human peripheral blood lymphocytes.
Fusion Partners
Target Species
Human
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Other Notes
Small volumes of anti-CD2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CD2 antibody
Mouse anti Human CD2 antibody, clone LT2 recognizes human CD2, a single chain transmembrane glycoprotein of 50kD, expressed by T cells, NK cells and thymocytes. CD2 is a receptor for CD58 (LFA-3), and is important in mediating the interaction between T cells and target cells or antigen presenting cells. Mouse anti Human CD2 antibody, clone LT2 inhibits NK cell mediated cytotoxicity, and ConA and PHA mediated blast transformation.
Applications Tested/Suitable for anti-CD2 antibody
Flow cytometry (FC/FACS)
Application Notes for anti-CD2 antibody
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells or 100ul of whole blood using the lysed whole blood labelling method.
Flow Cytometry: Maximum Dilution: Neat

Testing Data of anti-CD2 antibody
Staining of human peripheral blood lymphocytes with Mouse anti Human CD2 (MBS212049)
anti-CD2 antibody Testing Data image
Testing Data of anti-CD2 antibody
Staining of human peripheral blood lymphocytes with Mouse anti Human CD2:Biotin
anti-CD2 antibody Testing Data image
Testing Data of anti-CD2 antibody
Staining of human peripheral blood lymphocytes with Mouse anti Human CD2:RPE (MBS213559)
anti-CD2 antibody Testing Data image
Testing Data of anti-CD2 antibody
Staining of human peripheral blood lymphocytes with Mouse anti Human CD2:Alexa Fluor 647 (MBS212049A647)
anti-CD2 antibody Testing Data image
Testing Data of anti-CD2 antibody
Staining of human peripheral blood lymphocytes with Mouse anti Human CD2:FITC (MBS210628)
anti-CD2 antibody Testing Data image
Testing Data of anti-CD2 antibody
Staining of human peripheral blood lymphocytes with Mouse anti Human CD2 (MBS212050)
anti-CD2 antibody Testing Data image
Testing Data of anti-CD2 antibody
Staining of human peripheral blood lymphocytes with Mouse anti Human CD2:Low Endotoxin (MBS219466)
anti-CD2 antibody Testing Data image
NCBI/Uniprot data below describe general gene information for CD2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
39,448 Da
NCBI Official Full Name
T-cell surface antigen CD2
NCBI Official Synonym Full Names
CD2 molecule
NCBI Official Symbol
NCBI Official Synonym Symbols
T11; SRBC; LFA-2
  [Similar Products]
NCBI Protein Information
T-cell surface antigen CD2; CD2 antigen (p50), sheep red blood cell receptor; LFA-3 receptor; T-cell surface antigen T11/Leu-5; erythrocyte receptor; lymphocyte-function antigen-2; rosette receptor
UniProt Protein Name
T-cell surface antigen CD2
UniProt Synonym Protein Names
Erythrocyte receptor; LFA-2; LFA-3 receptor; Rosette receptor; T-cell surface antigen T11/Leu-5; CD_antigen: CD2
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
UniProt Entry Name
CD2_HUMAN
NCBI Summary for CD2
CD2 is a surface antigen of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells (summarized by Sewell et al., 1986 [PubMed 3490670]). It is one of the earliest T-cell markers, being present on more than 95% of thymocytes; it is also found on some natural killer cells but not on B lymphocytes. Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it.[supplied by OMIM, Jul 2010]
UniProt Comments for CD2
CD2: CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T- cells, the cytoplasmic domain is implicated in the signaling function.

Protein type: Apoptosis; Cell surface; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p13.1

Cellular Component: internal side of plasma membrane; cell surface; anchored to plasma membrane; integral to plasma membrane; plasma membrane; extracellular region; intercellular junction; external side of plasma membrane

Molecular Function: protein binding; protein homodimerization activity; receptor activity; receptor binding

Biological Process: heterotypic cell-cell adhesion; cell-cell adhesion; cell surface receptor linked signal transduction; T cell activation; apoptosis; natural killer cell activation; regulation of T cell differentiation; lipid raft polarization; blood coagulation; positive regulation of tumor necrosis factor production; positive regulation of myeloid dendritic cell activation; leukocyte migration
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000