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anti-CD2 antibody :: Mouse CD2 Monoclonal Antibody

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Catalog # MBS219663
Unit / Price
  100 Tests  /  $515 +1 FREE 8GB USB
anti-CD2 antibody
Product Name

CD2, Monoclonal Antibody

Popular Item
Also Known As

MOUSE ANTI HUMAN CD2:RPE

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
351
OMIM
186990
3D Structure
ModBase 3D Structure for P06729
Clonality
Monoclonal
Isotype
IgG1
Clone Number
RPA-2.10
Host
Mouse
Form/Format
Purified IgG conjugated to RPE - liquid
Perservative Stabilisers
0.09% Sodium Azide
0.2% Bovine Serum Albumin
Preparation
Buffer Solution
Phosphate buffered saline
Target Species
Human
Preparation and Storage
Store at 4 degree C. DO NOT FREEZE. This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 6 months from date of despatch.
Other Notes
Small volumes of anti-CD2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CD2 antibody
Mouse anti Human CD2 antibody, clone RPA-2.10 recognizes the human CD2 cell surface antigen. CD2 is expressed by T lymphocytes and by NK cells.
Applications Tested/Suitable for anti-CD2 antibody
Flow cytometry (FC/FACS)
Application Notes for anti-CD2 antibody
Flow Cytometry: Use 20ul of the suggested working dilution to label 106 cells or 100ul whole blood.
Flow Cytometry: Maximum Dilution: Neat
NCBI/Uniprot data below describe general gene information for CD2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
39,448 Da
NCBI Official Full Name
T-cell surface antigen CD2
NCBI Official Synonym Full Names
CD2 molecule
NCBI Official Symbol
NCBI Official Synonym Symbols
T11; SRBC; LFA-2
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NCBI Protein Information
T-cell surface antigen CD2; CD2 antigen (p50), sheep red blood cell receptor; LFA-3 receptor; T-cell surface antigen T11/Leu-5; erythrocyte receptor; lymphocyte-function antigen-2; rosette receptor
UniProt Protein Name
T-cell surface antigen CD2
UniProt Synonym Protein Names
Erythrocyte receptor; LFA-2; LFA-3 receptor; Rosette receptor; T-cell surface antigen T11/Leu-5; CD_antigen: CD2
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
UniProt Entry Name
CD2_HUMAN
NCBI Summary for CD2
CD2 is a surface antigen of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells (summarized by Sewell et al., 1986 [PubMed 3490670]). It is one of the earliest T-cell markers, being present on more than 95% of thymocytes; it is also found on some natural killer cells but not on B lymphocytes. Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it.[supplied by OMIM, Jul 2010]
UniProt Comments for CD2
CD2: CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T- cells, the cytoplasmic domain is implicated in the signaling function.

Protein type: Apoptosis; Cell surface; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p13.1

Cellular Component: internal side of plasma membrane; cell surface; anchored to plasma membrane; integral to plasma membrane; extracellular region; plasma membrane; intercellular junction; external side of plasma membrane

Molecular Function: protein binding; protein homodimerization activity; receptor activity; receptor binding

Biological Process: heterotypic cell-cell adhesion; cell-cell adhesion; cell surface receptor linked signal transduction; T cell activation; apoptosis; natural killer cell activation; regulation of T cell differentiation; lipid raft polarization; positive regulation of tumor necrosis factor production; blood coagulation; leukocyte migration; positive regulation of myeloid dendritic cell activation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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