NP_766235.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
32,424 Da
NCBI Official Full Name
junctional adhesion molecule A
NCBI Official Synonym Full Names
F11 receptor
NCBI Official Synonym Symbols
JAM; Jcam; JAM-1; JAM-A; Jcam1; Ly106; ESTM33; AA638916; 9130004G24 [Similar Products]
NCBI Protein Information
junctional adhesion molecule A; BV11 antigen; F11 receptor/F11R; junction cell adhesion molecule A; junction cell adhesion molecule1; junctional adhesion molecule 1
UniProt Protein Name
Junctional adhesion molecule A
UniProt Synonym Protein Names
Junctional adhesion molecule 1; JAM-1; CD_antigen: CD321
UniProt Synonym Gene Names
UniProt Entry Name
JAM1_MOUSE
UniProt Comments for CD321
JAM-A: Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus. Belongs to the immunoglobulin superfamily.
Protein type: Cell adhesion; Membrane protein, integral
Cellular Component: microtubule cytoskeleton; tight junction; membrane; integral to membrane; plasma membrane; cytoplasmic vesicle; intercellular junction; cell junction
Molecular Function: protein binding; PDZ domain binding
Biological Process: epithelial cell differentiation; viral reproduction; actomyosin structure organization and biogenesis; cell adhesion; positive regulation of blood pressure; intestinal absorption
Research Articles on CD321
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Products associated with anti-CD321 antibody
Pathways associated with anti-CD321 antibody
Diseases associated with anti-CD321 antibody
Organs/Tissues associated with anti-CD321 antibody
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