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anti-CD38 antibody :: Mouse CD38 Monoclonal Antibody

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Catalog # MBS210596
Unit / Price
  0.1 mg  /  $375 +1 FREE 8GB USB
Product Name

CD38, Monoclonal Antibody

Popular Item
Full Product Name

MOUSE ANTI HUMAN CD38:FITC

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
107270
3D Structure
ModBase 3D Structure for P28907
Clonality
Monoclonal
Isotype
IgG1
Clone Number
AT13/5
Host
Mouse
Form/Format
FITC
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
Concentration
IgG concentration 0.1 mg/ml (lot specific)
Perservative Stabilisers
0.09% Sodium Azide
1% Bovine Serum Albumin
Preparation
Purified IgG prepared by affinity chromatography on Protein A
Immunogen
Namalwa human B-cell line
Fusion Partners
Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.
Buffer Solution
Phosphate buffered saline
Target Species
Human
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Other Notes
Small volumes of anti-CD38 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CD38 antibody
Mouse anti Human CD38 antibody, clone AT13/5 recognizes a 45kDa glycoprotein and has a reactivity pattern consistent with antibodies of the CD38 cluster. CD38 is expressed by plasma cells, monocytes, early lymphoid cells and activated T cells. CD38 is widely used to study the processes of B and T differentiation and activation. Recently CD38 has been shown to possess ADP-ribosyl cyclase activity.
Applications Tested/Suitable for anti-CD38 antibody
Flow cytometry (FC/FACS)
Application Notes for anti-CD38 antibody
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells or 100ul whole blood.
Flow Cytometry: Maximum Dilution: Neat

Testing Data of anti-CD38 antibody
Staining of human peripheral blood lymphocytes with Mouse anti Human CD38:Alexa Fluor 647 (MBS211993A647)
anti-CD38 antibody Testing Data image
Testing Data of anti-CD38 antibody
Staining of human peripheral blood monocytes with Mouse anti Human CD38:Biotin (MBS210303)
anti-CD38 antibody Testing Data image
Testing Data of anti-CD38 antibody
Staining of human peripheral blood lymphocytes with Mouse anti Human CD38:Biotin (MBS210303)
anti-CD38 antibody Testing Data image
Testing Data of anti-CD38 antibody
Staining of human peripheral blood monocytes with Mouse anti Human CD38:RPE-Alexa Fluor 750 (MBS211993P750)
anti-CD38 antibody Testing Data image
Testing Data of anti-CD38 antibody
Staining of human peripheral blood monocytes with Mouse anti Human CD38:RPE (MBS213537)
anti-CD38 antibody Testing Data image
Testing Data of anti-CD38 antibody
Staining of human peripheral blood monocytes with Mouse anti Human CD38:RPE (MBS213537)
anti-CD38 antibody Testing Data image
Testing Data of anti-CD38 antibody
Staining of human peripheral blood monocytes using Mouse anti Human CD38:FITC
anti-CD38 antibody Testing Data image
Testing Data of anti-CD38 antibody
Staining of human peripheral blood monocytes with Mouse anti Human CD38:Azide Free (MBS210116)
anti-CD38 antibody Testing Data image
NCBI/Uniprot data below describe general gene information for CD38. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
NCBI Official Synonym Full Names
CD38 molecule
NCBI Official Symbol
NCBI Official Synonym Symbols
T10; ADPRC 1
  [Similar Products]
NCBI Protein Information
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; 2'-phospho-ADP-ribosyl cyclase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; ADP-ribosyl cyclase 1; CD38 antigen (p45); NAD(+) nucleosidase; cADPr hydrolase 1
UniProt Protein Name
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
UniProt Synonym Protein Names
2'-phospho-ADP-ribosyl cyclase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase (EC:2.4.99.20); 2'-phospho-cyclic-ADP-ribose transferase; ADP-ribosyl cyclase 1; ADPRC 1; Cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; T10; CD_antigen: CD38
UniProt Gene Name
UniProt Synonym Gene Names
ADPRC 1; cADPr hydrolase 1  [Similar Products]
UniProt Entry Name
CD38_HUMAN
NCBI Summary for CD38
CD38 is a novel multifunctional ectoenzyme widely expressed in cells and tissues especially in leukocytes. CD38 also functions in cell adhesion,signal transduction and calcium signaling. [provided by RefSeq, Jul 2008]
UniProt Comments for CD38
CD38: Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system. Belongs to the ADP-ribosyl cyclase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.2.2.6; Lyase; Hydrolase; Apoptosis; EC 2.4.99.20; Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; Cell surface; Membrane protein, integral; Cell cycle regulation

Chromosomal Location of Human Ortholog: 4p15

Cellular Component: cell surface; membrane; plasma membrane; integral to membrane; nucleus

Molecular Function: transferase activity; phosphorus-oxygen lyase activity; NAD+ nucleosidase activity; NAD(P)+ nucleosidase activity

Biological Process: response to drug; response to retinoic acid; metabolic process; positive regulation of transcription, DNA-dependent; positive regulation of insulin secretion; female pregnancy; signal transduction; positive regulation of cell growth; response to estradiol stimulus; elevation of cytosolic calcium ion concentration; B cell receptor signaling pathway; response to hydroperoxide; positive regulation of vasoconstriction; positive regulation of B cell proliferation; response to hypoxia; negative regulation of transcription, DNA-dependent; response to progesterone stimulus; negative regulation of bone resorption; negative regulation of apoptosis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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