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anti-CD66e antibody :: Mouse CD66e Monoclonal Antibody

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Catalog # MBS211505
Unit / Price
  0.2 mg  /  $350 +1 FREE 8GB USB
anti-CD66e antibody
Product Name

CD66e, Monoclonal Antibody

Popular Item
Full Product Name

MOUSE ANTI HUMAN CD66e

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
114890
3D Structure
ModBase 3D Structure for P06731
Clonality
Monoclonal
Isotype
IgG1
Clone Number
CB30
Host
Mouse
Form/Format
Purified
Purified IgG - liquid
Concentration
Approximate Protein Concentration: 1.0 mg/ml (lot specific)
Perservative Stabilisers
0.09% Sodium Azide (NaN3)
Preparation
Histology Positive Control Tissue
Adenocarcinoma of colon.
Buffer Solution
Target Species
Human
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Other Notes
Small volumes of anti-CD66e antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CD66e antibody
Mouse anti Human CD66e antibody, clone CB30 recognizes human CD66e, also known as carcinoembryonic antigen (CEA). CD66e is a member of the immunoglobulin supergene family that is mainly expressed on epithelial cells. CD66e may play a role in cancer cells metastasis, and has been used clinically as a tumor marker for early detection of disease.
Applications Tested/Suitable for anti-CD66e antibody
Immunohistology Frozen, Flow cytometry (FC/FACS), Immunoprecipitation (IP), Immunohistology Paraffin*
Application Notes for anti-CD66e antibody
Immunohistology - Paraffin: Minimum Dilution: 1/100; Maximum Dilution: 1/200; Application Note: This product requires protein digestion pre-treatment of paraffin sections e.g. pronase.
NCBI/Uniprot data below describe general gene information for CD66e. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
76,724 Da
NCBI Official Full Name
carcinoembryonic antigen-related cell adhesion molecule 5 preproprotein
NCBI Official Synonym Full Names
carcinoembryonic antigen-related cell adhesion molecule 5
NCBI Official Symbol
CEACAM5  [Similar Products]
NCBI Official Synonym Symbols
CEA; CD66e
  [Similar Products]
NCBI Protein Information
carcinoembryonic antigen-related cell adhesion molecule 5; meconium antigen 100
UniProt Protein Name
Carcinoembryonic antigen-related cell adhesion molecule 5
UniProt Synonym Protein Names
Carcinoembryonic antigen; CEA; Meconium antigen 100; CD_antigen: CD66e
UniProt Gene Name
CEACAM5  [Similar Products]
UniProt Synonym Gene Names
CEA; CEA  [Similar Products]
UniProt Entry Name
CEAM5_HUMAN
NCBI Summary for CD66e
Members of the CEACAM subfamily, including CEACAM5, belong to the CEA gene family. For general information on the CEA gene family, see CEACAM1 (MIM 109770).[supplied by OMIM, Oct 2009]
UniProt Comments for CD66e
CEACAM5: Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins. Homodimer. Binding of E.coli Dr adhesins leads to dissociation of the homodimer. Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon. Belongs to the immunoglobulin superfamily. CEA family.

Protein type: Membrane protein, integral; Immunoglobulin superfamily; Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 19q13.1-q13.2

Cellular Component: integral to plasma membrane; basolateral plasma membrane

Molecular Function: identical protein binding; protein homodimerization activity

Biological Process: homotypic cell-cell adhesion; negative regulation of apoptosis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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