CAA34902.2
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UniProt Primary Accession #
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NCBI Official Full Name
epidermal growth factor
UniProt Protein Name
Epidermal growth factor
UniProt Entry Name
Q8NDU8_HUMAN
NCBI Summary for EGFR
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
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Products associated with anti-EGFR antibody
Pathways associated with anti-EGFR antibody
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