• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-Lpro antibody :: Mouse FOOT-AND-MOUTH DISEASE VIRUS NON-STRUCTURAL PROTEIN 3a Monoclonal Antibody

Scan QR to view Datasheet
Catalog # MBS216325
Unit / Price
Scan QR to view Datasheet
  0.2 mg  /  $430 +1 FREE 8GB USB
anti-Lpro antibody
Product Name

FOOT-AND-MOUTH DISEASE VIRUS NON-STRUCTURAL PROTEIN 3a (Lpro), Monoclonal Antibody

Full Product Name

MOUSE ANTI FOOT-AND-MOUTH DISEASE VIRUS NON-STRUCTURAL PROTEIN 3a

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P49303
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
1G2
Host
Mouse
Form/Format
Purified
Purified IgG - liquid
Concentration
IgG concentration 1.0 mg/ml (lot specific)
Perservative Stabilisers
0.09% Sodium Azide
Preparation
Immunogen
Recombinant FMDV non structural protein 3a.
Buffer Solution
Target Species
Viral
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Other Notes
Small volumes of anti-Lpro antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-Lpro antibody
Mouse anti Foot-and-Mouth Disease Virus Non-Structural Protein 3a antibody, clone 1G2 recognizes the 3a non-structural protein of Foot-and-mouth disease virus (FMDV). Foot-and-mouth disease virus is a nonenveloped icosahedral Aphthovirus that contains single-stranded RNA. Foot-and-mouth disease is a highly contagious and sometimes fatal disease of cattle, pigs and other cloven-hoofed animals. The disease is characterised by high fever and blisters inside the mouth and on the feet. Although it doesn't have a high mortality rate, the disease has debilitating effects, including weight loss and decrease in milk production, resulting in detrimental economic ramifications. The virus is spread through direct contact. The non-structural proteins are necessary for viral replication and as such mutations in this area are probably less well tolerated than in the rest of the genome. Non-structural proteins have been targeted as possible diagnostic targets to distinguish between infected and vaccinated animals.
Applications Tested/Suitable for anti-Lpro antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for Lpro. It may not necessarily be applicable to this product.
NCBI GI #
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
Molecular Weight
256,785 Da[Similar Products]
NCBI Official Full Name
Genome polyprotein
UniProt Protein Name
Genome polyprotein
UniProt Synonym Protein Names
VP4-VP2
UniProt Gene Name
UniProt Synonym Gene Names
P2A; P2B; P2C; P3A; P3B-1; P3B-2; P3B-3; P3C; P3D-POL  [Similar Products]
UniProt Entry Name
POLG_FMDVZ
UniProt Comments for Lpro
The leader protease autocatalytically cleaves itself from the polyprotein at the L/VP0 junction. It cleaves the host translation initiation factors EIF4G1 and EIF4G3, in order to shut down the capped cellular mRNA transcription. Increases translation driven by the viral internal ribosome entry site (IRES).
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000