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anti-GCSF antibody :: Granylocyte colony stimulating factor Monoclonal Antibody

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Catalog # MBS660033
Unit / Price
  1 mg  /  $660 +1 FREE 8GB USB
anti-GCSF antibody
Product Name

Granylocyte colony stimulating factor (GCSF), Monoclonal Antibody

Also Known As

Monoclonal mouse anti-Human Granulocyte Colony Stimulating Factor (GCSF)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
168
OMIM
138970
Clonality
Monoclonal
Isotype
IgG1 for MAbs GSB2, GSB3
IgG2a for MAb GSF12
IgG2b for MAbs CF-C8, CF-A1, GSA1
Clone Number
CF-C8, CF-A1; New MAbs: GSA1, GSB2, GSB3, GSF12
Specificity
Human Granuldegree Cyte Colony Stimulating Factor (GCSF)
Purity/Purification
Chromatography on protein G Sepharose
Form/Format
PBS, pH 7.2, 0.1 % sodium azide (NaN3)
Clone Note
Hybridoma clones have been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with recombinant GCSF.
Preparation and Storage
4 degree C
Other Notes
Small volumes of anti-GCSF antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Application Notes for anti-GCSF antibody
MAbs are working in ELISA.
Recommended pair for sandwich immunoassay are (capture - detection): GSB2 - GSB3, GSB2 - GSF12, GSF12 - GSA1, CF-C8 - CF-A1.
NCBI/Uniprot data below describe general gene information for GCSF. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
18,434 Da
NCBI Official Full Name
granulocyte colony-stimulating factor isoform d
NCBI Official Synonym Full Names
colony stimulating factor 3 (granulocyte)
NCBI Official Symbol
NCBI Official Synonym Symbols
GCSF; CSF3OS; C17orf33
  [Similar Products]
NCBI Protein Information
granulocyte colony-stimulating factor; filgrastim; lenograstim; pluripoietin; granulocyte-colony stimulating factor
UniProt Protein Name
Granulocyte colony-stimulating factor
UniProt Synonym Protein Names
Pluripoietin; INN: Filgrastim; INN: Lenograstim
UniProt Gene Name
UniProt Synonym Gene Names
C17orf33; GCSF; G-CSF  [Similar Products]
UniProt Entry Name
CSF3_HUMAN
NCBI Summary for GCSF
The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes. The active protein is found extracellularly. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2010]
UniProt Comments for GCSF
G-CSF: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes. Belongs to the IL-6 superfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation; Secreted; Cytokine; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 17q11.2-q12

Cellular Component: extracellular space

Molecular Function: enzyme binding; growth factor activity; cytokine activity; granulocyte colony-stimulating factor receptor binding

Biological Process: positive regulation of phosphoinositide 3-kinase cascade; positive regulation of protein kinase B signaling cascade; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of myeloid cell differentiation; positive regulation of actin filament polymerization; positive regulation of protein binding; granulocyte differentiation; multicellular organismal development; cytokine and chemokine mediated signaling pathway; positive regulation of cell proliferation; positive regulation of transcription factor import into nucleus; immune response; positive regulation of transcription from RNA polymerase II promoter; positive regulation of peptidyl-serine phosphorylation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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