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anti-HFE antibody :: Mouse HFE Monoclonal Antibody

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Catalog # MBS8527525
Unit / Price
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  0.1 mL  /  $290 +1 FREE 8GB USB
anti-HFE antibody
Product Name

HFE, Monoclonal Antibody

Full Product Name

Mouse Monoclonal Antibody to HFE

Product Synonym Names
HH; HFE1; HLA-H; MVCD7; TFQTL2; MGC103790; dJ221C16.10.1
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
176200
Clonality
Monoclonal
Isotype
IgG1
Clone Number
3F1D10
Host
Mouse
Other Notes
Small volumes of anti-HFE antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-HFE antibody
Western Blot (WB), Immunocytochemistry (ICC)
Application Notes for anti-HFE antibody
Western blot using Recombinant protein
Western blot using Transfection expressed protein
NCBI/Uniprot data below describe general gene information for HFE. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
40kDa
NCBI Official Full Name
HFE, partial
NCBI Official Synonym Full Names
homeostatic iron regulator
NCBI Official Symbol
NCBI Official Synonym Symbols
HH; HFE1; HLA-H; MVCD7; TFQTL2
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NCBI Protein Information
hereditary hemochromatosis protein
UniProt Protein Name
Hereditary hemochromatosis protein
UniProt Synonym Protein Names
HLA-H
UniProt Gene Name
UniProt Synonym Gene Names
NCBI Summary for HFE
The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
UniProt Comments for HFE
Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with anti-HFE antibody
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