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Mouse Hsp60 Monoclonal Antibody

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Catalog # MBS190473
Unit / Price
  0.1 mg  /  $235 +1 FREE 8GB USB
anti-Hsp60 antibody
Product Name

Hsp60, Monoclonal Antibody

Popular Item
Also Known As

Anti-Hsp60 Monoclonal Antibody

Product Synonym Names
Anti-Hsp60; Hsp60
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Clonality
Monoclonal
Isotype
IgG1
Host
Mouse
Specificity
Anti-Hsp60 [Mouse monoclonal antibody to human Hsp60]
This antibody recognizes human, mouse, rat, rabbit, bovine, canine, porcine, ovine, guinea pig, hamster, chicken, monkey, Xenopus, and Drosophila Hsp60 (60 kDa). It does not cross-react with bacterial or yeast Hsp60. The epitope recognized is within aa 383-447 of human Hsp60.
Form/Format
100ug in PBS, pH 7.4, purified by Protein G affinity chromatography.
Antigen
Recombinant human Hsp60 expressed in E. coli.
Preservatives
0.09% sodium azide
Other Additives
50% glycerol
Dilutions Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Avoid repeated freezing and thawing.
Other Notes
Small volumes of anti-Hsp60 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-Hsp60 antibody
Hsp60 is an abundant protein synthesized constitutively in various cell types that is induced to higher concentrations after cell shock. It is present in mitochondria of many mammalian species and has highly similar counterparts in bacteria and plants (where it is localized to chloroplasts). In general, Hsp60 proteins are present in high concentrations, are induced in response to environmental stresses (such as heat shock) are homo-oligomeric structures of 7 or 14 subunits that dissociate reversibly in the presence of Mg2+ and ATP, have ATPase activity, and play a role in folding and assembly of oligomeric protein structures. Hsp60 has been linked to Alzheimer's disease, coronary artery disease, multiple sclerosis, diabetes, and other autoimmune diseases.
Product Categories/Family for anti-Hsp60 antibody
Applications Tested/Suitable for anti-Hsp60 antibody
Flow Cytometry, Immunoblot, Immunoprecipitation
Application Notes for anti-Hsp60 antibody
Immunoblotting: use at 0.1-1ug/ml. A band of ~60 kDa is detected.
Immunoprecipitation: use at 12.5ug/ml
Flow cytometry: use at 10ug/ml These are recommended concentrations. User should determine optimal concentrations for their application.
Positive control: Heat-shocked HeLa cell lysate.
NCBI/Uniprot data below describe general gene information for Hsp60. It may not necessarily be applicable to this product.
NCBI GI #
NCBI Accession #
NCBI Official Full Name
HSP60
Protein Family
UniProt Comments for Hsp60
Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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