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Mouse Human Procollagen Type I C-Peptide (PIP) Monoclonal Antibody

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Catalog # MBS190258
Unit / Price
  0.1 mg  /  $410 +1 FREE 8GB USB
anti-Human Procollagen Type I C-Peptide (PIP) antibody
Product Name

Human Procollagen Type I C-Peptide (PIP), Monoclonal Antibody

Popular Item
Full Product Name

Human Procollagen Type I C-Peptide (PIP) Monoclonal Antibody

Product Synonym Names
Human Procollagen Type I C-Peptide (PIP); Procollagen Type I C-Peptide (PIP)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Clonality
Monoclonal
Isotype
IgG1
Host
Mouse
Specificity
These antibodies recognize non-denatured human, bovine, canine, and equine Procollagen Type I C-peptide. They do not react with rat or rabbit Procollagen Type 1 C-peptide.
Form/Format
100 ug IgG in 10mM PBS, pH 7.4, 1% BSA, lyophilized.
Antigen
Human Procollagen Type I C-Peptide.
Apperance
White Powder
Preparation and Storage
This product does not contain preservative. The stock solution (2.0mg/ml) can be stored in aliquots at -20°C for 1 year or can be stored at 4°C for 6 months after adding 0.1% sodium azide. Dilutions of stock solution should not be stored. Avoid repeated freeze-thaw cycles.
Other Notes
Small volumes of anti-Human Procollagen Type I C-Peptide (PIP) antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Collagens (types I, II, III, IV, and V) are synthesized as precursor molecules called procollagens. These contain additional peptide sequences, the “propeptides”, at the amino- and carboxy- terminal ends. Propeptides facilitate the winding of procollagen molecules into a triple-helix conformation within the endoplasmic reticulum. These propeptides are cleaved from the collagen triple helix during its secretion after which the collagens polymerize into extracellular collagen fibrils. Therefore, the amount of free propeptides correlates directly with collagen molecule synthesis. Procollagen Type I C-peptide (PIP) has been extensively referenced in studies that correlated collagen levels and disorders such as bone disease, alcoholic liver disease, liver cirrhosis, and scirrhous (Borrmann type IV) adenocarcinoma of the stomach.
ELISA, Western Blot, Immunohistochemistry
ELISA: 0.2ug/ml with solid phase antigen. For sandwich ELISA, use MBS190258 on the solid phase and labeled MBS190258 for detection of binding.

Western Blot: 10ug/ml under non-reducing and non-heating conditions.

Immunohistochemistry: 10ug/ml on cultured cells, frozen and paraffin-embedded tissue sections (Antigen retrieval: Proteinase K treatment)

Dissolve lyophilized antibody in 50 uL of distilled water (final concentration 2.0 mg/mL).
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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