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anti-IFN-g antibody :: Mouse Interferon-gamma Monoclonal Antibody

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Catalog # MBS140024
Unit / Price
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  0.5 mg  /  $305 +1 FREE 8GB USB
  1 mg  /  $455 +1 FREE 8GB USB
anti-IFN-g antibody
Product Name

Interferon-gamma (IFN-g), Monoclonal Antibody

Popular Item
Full Product Name

Mouse Anti Human Interferon-gamma

Product Synonym Names
IFN g Antibody; Interferon-gamma, Mouse Anti-Human; Immune Interferon; type II interferon; T cell interferon; MAF; IFNG; IFG; IFI; IFN-gamma
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
NYRhIFNg
Host
Mouse
Purity/Purification
Ion exchange.
Concentration
1mg/ml in PBS (after reconstitution). (lot specific)
Reconstitution
Reconstitute with sterile H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
Immunogen
r.Human IFN-g.
Preparation and Storage
In lyophilized form, for long periods, store at 4C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20C.
Antibody is shipped lyophilized at ambient temperature.
Other Notes
Small volumes of anti-IFN-g antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-IFN-g antibody
Introduction: IFN-gamma produced by lymphocytes activated by specific antigens or mitogens.IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activator of macrophages, and has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
Applications Tested/Suitable for anti-IFN-g antibody
ELISA (EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Intracellular Staining
Application Notes for anti-IFN-g antibody
Direct ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry, Intracellular staining.
This antibody loses its antigen binding capacity when immobilized on plastic. Biological activity is determined by virus neutralization assay and MHC class II induction.
NCBI/Uniprot data below describe general gene information for IFN-g. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
17,907 Da
NCBI Official Full Name
interferon gamma
NCBI Official Synonym Full Names
interferon gamma
NCBI Official Symbol
NCBI Official Synonym Symbols
Ifg; IFN-g
  [Similar Products]
NCBI Protein Information
interferon gamma; IFN-gamma; gamma interferon
UniProt Protein Name
Interferon gamma
UniProt Gene Name
UniProt Synonym Gene Names
IFN-gamma  [Similar Products]
UniProt Entry Name
IFNG_MOUSE
NCBI Summary for IFN-g
This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of the both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial inflections. Mice deficient in this gene have increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Sep 2015]
UniProt Comments for IFN-g
IFNG: Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. Homodimer. Released primarily from activated T lymphocytes. Belongs to the type II (or gamma) interferon family.

Protein type: Membrane protein, integral; Cytokine; Secreted; Secreted, signal peptide

Cellular Component: extracellular space; cell; extracellular region; intracellular; external side of plasma membrane

Molecular Function: protein binding; interferon-gamma receptor binding; cytokine activity

Biological Process: positive regulation of isotype switching to IgG isotypes; positive regulation of nitric oxide biosynthetic process; positive regulation of cell adhesion; positive regulation of osteoclast differentiation; positive regulation of interleukin-23 production; positive regulation of transcription, DNA-dependent; negative regulation of epithelial cell differentiation; positive regulation of interleukin-1 beta secretion; positive regulation of killing of cells of another organism; positive regulation of membrane protein ectodomain proteolysis; regulation of growth; positive regulation of T cell proliferation; cell cycle arrest; defense response to virus; regulation of the force of heart contraction; positive regulation of peptidyl-serine phosphorylation of STAT protein; neutrophil chemotaxis; positive regulation of synaptic transmission, cholinergic; negative regulation of myelination; CD8-positive, alpha-beta T cell differentiation during immune response; response to virus; defense response to protozoan; positive regulation of tumor necrosis factor production; inflammatory cell apoptosis; positive regulation of tyrosine phosphorylation of Stat1 protein; defense response to bacterium; neutrophil apoptosis; positive regulation of transcription from RNA polymerase II promoter; positive regulation of interleukin-12 production; apoptosis; negative regulation of smooth muscle cell proliferation; positive regulation of interleukin-6 biosynthetic process; negative regulation of transcription from RNA polymerase II promoter; sensory perception of mechanical stimulus; negative regulation of cell proliferation; regulation of transcription, DNA-dependent; positive regulation of MHC class II biosynthetic process; positive regulation of cell proliferation; adaptive immune response; regulation of immune response; unfolded protein response; humoral immune response; antigen processing and presentation; negative regulation of interleukin-17 production; positive regulation of interleukin-12 biosynthetic process; positive regulation of chemokine biosynthetic process; protein import into nucleus, translocation; immune response; positive regulation of neuron differentiation; regulation of insulin secretion
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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