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anti-H2-K1 antibody :: Mouse MHC CLASS I H-2Kb Monoclonal Antibody

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Catalog # MBS219553
Unit / Price
  0.1 mg  /  $240 +1 FREE 8GB USB
anti-H2-K1 antibody
Product Name

MHC CLASS I H-2Kb (H2-K1), Monoclonal Antibody

Also Known As

MOUSE ANTI MOUSE MHC CLASS I H-2Kb:FITC

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
369
3D Structure
ModBase 3D Structure for P01901
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
AF6-88.5
Host
Mouse
Form/Format
FITC
Purified IgG conjugated to fluorescein isothiocyanate (FITC) - liquid.
Concentration
IgG concentration 0.5mg/ml (lot specific)
Perservative Stabilisers
0.09% Sodium Azide (NaN3)
Preparation
Immunogen
C57BL mouse splenocytes
Buffer Solution
Target Species
Mouse
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Other Notes
Small volumes of anti-H2-K1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-H2-K1 antibody
Mouse anti Mouse MHC Class I H-2Kb antibody, clone AF6-88.5 recognizes the H-2Kb determinant present on all nucleated cells of mice expressing this MHC class I haplotype. The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In mice, this complex is referred to as the histocompatibility 2 (H-2) region. There are 3 major MHC class I proteins encoded by the H-2 which are H-2K, H-2L and H-2D. The H- 2K gene is part of the murine H-2 complex on chromosome 17 and there are a large number of variant alleles of this gene. Mouse anti Mouse MHC Class I H-2Kb antibody, clone AF6-88.5 does not cross react with other haplotypes.
Applications Tested/Suitable for anti-H2-K1 antibody
Flow cytometry (FC/FACS)
Application Notes for anti-H2-K1 antibody
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul.
Flow Cytometry: Minimum Dilution: 1/10; Maximum Dilution: 1/20
NCBI/Uniprot data below describe general gene information for H2-K1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
41,302 Da[Similar Products]
NCBI Official Full Name
H-2 class I histocompatibility antigen, K-W28 alpha chain isoform 1
NCBI Official Synonym Full Names
histocompatibility 2, K1, K region
NCBI Official Symbol
H2-K1  [Similar Products]
NCBI Official Synonym Symbols
K-f; H-2K; H2-K; H-2K(d)
  [Similar Products]
NCBI Protein Information
H-2 class I histocompatibility antigen, K-W28 alpha chain; H-2 class I histocompatibility antigen, K-B alpha chain; H-2 class I histocompatibility antigen, K-D alpha chain; H-2 class I histocompatibility antigen, K-K alpha chain; H-2 class I histocompatibility antigen, K-Q alpha chain; H-2K(B); H-2K(K); H-2K(Q); MHC H2-K transplantation antigen; MHC class I H2-K-b-alpha-2 cell surface glycoprotein; MHC class I antigen; MHC class I heavy chain H2-K; class I major histocompatibility antigen H-2Kd
UniProt Protein Name
H-2 class I histocompatibility antigen, K-B alpha chain
UniProt Gene Name
H2-K1  [Similar Products]
UniProt Synonym Gene Names
H2-K; H-2K(B)  [Similar Products]
UniProt Entry Name
HA1B_MOUSE
UniProt Comments for H2-K1
HLAC iso22: Involved in the presentation of foreign antigens to the immune system. Belongs to the MHC class I family.

Protein type: Membrane protein, integral; Receptor, misc.

Cellular Component: Golgi apparatus; cell surface; membrane; endoplasmic reticulum; integral to membrane; MHC class I protein complex; Golgi medial cisterna; external side of plasma membrane

Molecular Function: protein binding; peptide antigen binding; beta-2-microglobulin binding; protein heterodimerization activity; T cell receptor binding; peptide binding; TAP binding; receptor binding

Biological Process: antigen processing and presentation; antigen processing and presentation of peptide antigen via MHC class I; immune system process; positive regulation of T cell mediated cytotoxicity; defense response to bacterium; antigen processing and presentation of exogenous peptide antigen via MHC class I; immune response; inner ear development; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Diseases associated with anti-H2-K1 antibody
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