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anti-MUCIN 2 antibody :: Mouse MUCIN 2 Monoclonal Antibody

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Catalog # MBS216981
Unit / Price
  0.1 mg  /  $375 +1 FREE 8GB USB
anti-MUCIN 2 antibody
Product Name

MUCIN 2, Monoclonal Antibody

Popular Item
Also Known As

MOUSE ANTI HUMAN MUCIN 2:FITC

Product Synonym Names
MUC-2, SMUC
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
5179
OMIM
158370
3D Structure
ModBase 3D Structure for Q02817
Clonality
Monoclonal
Isotype
IgG1
Clone Number
996/1
Host
Mouse
Specificity
Mouse anti Human Muccin 2 Antibody, clone 996/1 recognizes human Mucin 2 (MUC-2), and shows no cross-reactivity with MUC-1, MUC-3 or MUC-4. In formalin fixed, paraffin embedded tissue sections Mouse anti Human Mucin 2 antibody, clone 996/1 recognizes colon, liver and prostate tissues strongly. The antibody recognizes malignant colonic mucosa as well as normal mucosa.
Form/Format
FITC
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
Concentration
IgG concentration 0.1 mg/ml (lot specific)
Perservative Stabilisers
0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
Preparation
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen
MUC-2 tandem repeat peptide.
Buffer Solution
Phosphate buffered saline
Target Species
Human
Fusion Partners
Spleen cells from immunised Balb/c mice were fused with cells of a mouse NS0 myeloma cell line.
Max Ex/Em
Fluorophore: FITC
Excitation (nm): 490
Emission (nm): 520
Preparation and Storage
Store at 4°C or -20°C if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Other Notes
Small volumes of anti-MUCIN 2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-MUCIN 2 antibody
Mouse anti Human Mucin 2 antibody, clone 996/1 recognizes human Mucin 2 (MUC-2), and shows no cross-reactivity with MUC-1, MUC-3 or MUC-4. In tissue sections Mouse anti Human Mucin 2 antibody, clone 996/1 recognizes colon, liver and prostate tissues strongly. The antibody recognizes malignant colonic mucosa as well as normal mucosa.
Applications Tested/Suitable for anti-MUCIN 2 antibody
Flow cytometry
Application Notes for anti-MUCIN 2 antibody
Suggested Dilution: Neat-1/10

Flow Cytometry: Use 10ul of the suggested working dilution to label 1x106 cells in 100ul.
NCBI/Uniprot data below describe general gene information for MUCIN 2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
mucin-2
NCBI Official Synonym Full Names
mucin 2, oligomeric mucus/gel-forming
NCBI Official Symbol
NCBI Official Synonym Symbols
MLP; SMUC; MUC-2
  [Similar Products]
NCBI Protein Information
mucin-2; intestinal mucin-2; mucin 2, intestinal/tracheal; mucin-like protein
UniProt Protein Name
Mucin-2
UniProt Synonym Protein Names
Intestinal mucin-2
UniProt Gene Name
UniProt Synonym Gene Names
SMUC; MUC-2  [Similar Products]
UniProt Entry Name
MUC2_HUMAN
NCBI Summary for MUCIN 2
This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2008]
UniProt Comments for MUCIN 2
MUC2: Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer.

Protein type: Secreted; Secreted, signal peptide; Extracellular matrix

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: Golgi lumen

Molecular Function: protein binding

Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; O-glycan processing; maintenance of gastrointestinal epithelium; post-translational protein modification
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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