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anti-PRL antibody :: Prolactin Monoclonal Antibody

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Catalog # MBS310611
Unit / Price
  5 mg  /  $1,400 +1 FREE 8GB USB
anti-PRL antibody
Product Name

Prolactin (PRL), Monoclonal Antibody

Also Known As

MAb to Human Prolactin

Product Synonym Names
Monoclonal Antibody to Human Prolactin
Product Gene Name
Matching Pairs
Matching Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
220
Chromosome Location
Chromosome: 6; NC_000006.11 (22287475..22303082, complement). Location: 6p22.2-p21.3
OMIM
176760
3D Structure
ModBase 3D Structure for P01236
Clonality
Monoclonal
Isotype
IgG1, kappa
Clone Number
ME.121
Host
Host: Mouse
Source: Ascites
Specificity
Prolactin
Recognizes the beta subunit of human prolactin. Specificity is tested by EIA.
Crossreactivity: Primary MAb - E20630M
Secondary MAb - E20122M
BhCG - <1%
hCG - <1%
hLH - <1%
hFSH - <1%
Prolactin - 100%
Purity/Purification
>95% pure. Protein A chromatography
Product is 0.22um filtered.
Form/Format
Purified, Liquid
Concentration
1.7mg/ml (OD280nm, E^0.1% = 1.36) (lot specific)
Immunogen
Human prolactin. MW 23kD
Affinity Constant
1 x 10^10
Buffer
0.15M PBS, pH 7.4
Preservative
No
Important Note
Centrifuge before opening to ensure complete recovery of vial contents.
Preparation and Storage
Short term (up to 1 month) store at 2 to 8 degree C. Long term, aliquot and store at -20 degree C to -80 degree C. Avoid multiple freeze/thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-PRL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-PRL antibody
Immunoassay Antibody Pairs
Application Notes for anti-PRL antibody
ELISA. Suitable for use as a capture or detection antibody in enzyme immunoassays. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not n
NCBI/Uniprot data below describe general gene information for PRL. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
25,876 Da[Similar Products]
NCBI Official Full Name
prolactin
NCBI Official Synonym Full Names
prolactin
NCBI Official Symbol
NCBI Official Synonym Symbols
NCBI Protein Information
prolactin; OTTHUMP00000017727
UniProt Protein Name
Prolactin
Protein Family
UniProt Gene Name
UniProt Entry Name
PRL_HUMAN
NCBI Summary for PRL
This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]
UniProt Comments for PRL
prolactin: Prolactin acts primarily on the mammary gland by promoting lactation. Belongs to the somatotropin/prolactin family.

Protein type: Motility/polarity/chemotaxis; Cytokine; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 6p22.3

Cellular Component: extracellular region

Molecular Function: protein binding; prolactin receptor binding; hormone activity

Biological Process: lactation; cell proliferation; cell surface receptor linked signal transduction; regulation of multicellular organism growth; positive regulation of JAK-STAT cascade; female pregnancy
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withanti-PRL antibody
 Reference Product  PubMed Publications
 PRLR antibody  >262 publications with PRL and PRLR
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