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anti-SRY antibody :: Mouse SRY Monoclonal Antibody

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Catalog # MBS8527640
Unit / Price
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  0.1 mL  /  $290 +1 FREE 8GB USB
anti-SRY antibody
Product Name

SRY, Monoclonal Antibody

Full Product Name

Mouse Monoclonal Antibody to SRY

Product Synonym Names
TDF; TDY; SRXX1; SRXY1
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
400044
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1G4E9
Host
Mouse
Immunogen
Full (1-204)
Other Notes
Small volumes of anti-SRY antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-SRY antibody
Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Application Notes for anti-SRY antibody
Western blot using Recombinant protein
Western blot using Cell lysate
NCBI/Uniprot data below describe general gene information for SRY. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Related Accession #
Molecular Weight
23.9kDa
NCBI Official Full Name
SRY, partial
NCBI Official Synonym Full Names
sex determining region Y
NCBI Official Symbol
NCBI Official Synonym Symbols
TDF; TDY; SRXX1; SRXY1
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NCBI Protein Information
sex-determining region Y protein
UniProt Protein Name
Sex-determining region Y protein
UniProt Synonym Protein Names
Testis-determining factor
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
NCBI Summary for SRY
This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome); translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome. [provided by RefSeq, Jul 2008]
UniProt Comments for SRY
Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (). Involved in different aspects of gene regulation including promoter activation or repression (). Promotes DNA bending. SRY HMG box recognizes DNA by partial intercalation in the minor groove. Also involved in pre-mRNA splicing. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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