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anti-SFTPD antibody :: Mouse SURFACTANT PROTEIN D Monoclonal Antibody

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Catalog # MBS219620
Unit / Price
  0.25 mg  /  $455 +1 FREE 8GB USB
Testing Data
Product Name

SURFACTANT PROTEIN D (SFTPD), Monoclonal Antibody

Popular Item
Also Known As

MOUSE ANTI PIG SURFACTANT PROTEIN D

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
378
3D Structure
ModBase 3D Structure for Q9N1X4
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1.7
Host
Mouse
Specificity
This item detects porcine surfactant protein D (pSP-D), a 138kD member of the collectin family of proteins. Surfactant protein D is thought to play a significant role in the innate immune response against microorganisms within the lungs and at other mucosal surfaces. SP-D is a multifunctional protein which binds selectively to saccharides and lipids on microbial surfaces promoting antimicrobial responses and regulating surfactant lipid homeostasis. SP-D expression is induced in lung surfactant in response to aerogenous bacterial infection, and upon binding to bacteria, promotes phagocytosis and antigen presentation by dendritic cells. Recent studies suggest that pSP-D could serve as a serum biomarker specific for bronchopneumonia in pigs.
Form/Format
Purified
Purified IgG - liquid
Concentration
IgG concentration 1.0mg/ml (lot specific)
Perservative Stabilisers
0.09% Sodium Azide (NaN3)
Preparation
Immunogen
Purified porcine surfactant protein D
Histology Positive Control Tissue
Target Species
Pig
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Other Notes
Small volumes of anti-SFTPD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SFTPD antibody
MBS219620 detects porcine surfactant protein D (pSP-D), a 138kD member of the collectin family of proteins. Surfactant protein D is thought to play a significant role in the innate immune response against microorganisms within the lungs and at other mucosal surfaces. SP-D is a multifunctional protein which binds selectively to saccharides and lipids on microbial surfaces promoting antimicrobial responses and regulating surfactant lipid homeostasis. SP-D expression is induced in lung surfactant in response to aerogenous bacterial infection, and upon binding to bacteria, promotes phagocytosis and antigen presentation by dendritic cells. Recent studies suggest that pSP-D could serve as a serum biomarker specific for bronchopneumonia in pigs.
Applications Tested/Suitable for anti-SFTPD antibody
Immunohistology Frozen, Immunofluorescence (IF), Immunohistology Paraffin*, Western Blot (WB)
Application Notes for anti-SFTPD antibody
Western Blot: This item detects a band of approximately 138kDa.
Immunohistology - Frozen: Minimum Dilution: 1ug/ml
Immunohistology - Paraffin: Application Note: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.

TRIS/EDTA buffer pH8.0 is recommended for this purpose.

Testing Data of anti-SFTPD antibody
Staining of frozen pig lung with Mouse anti pig Surfactant Protein D
anti-SFTPD antibody Testing Data image
NCBI/Uniprot data below describe general gene information for SFTPD. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
37,986 Da[Similar Products]
NCBI Official Full Name
pulmonary surfactant-associated protein D
NCBI Official Symbol
SFTPD  [Similar Products]
NCBI Official Synonym Symbols
SP-D; PSP-D
  [Similar Products]
NCBI Protein Information
pulmonary surfactant-associated protein D; lung surfactant protein D; surfactant, pulmonary-associated protein D
UniProt Protein Name
Pulmonary surfactant-associated protein D
UniProt Synonym Protein Names
Lung surfactant protein D
UniProt Gene Name
SFTPD  [Similar Products]
UniProt Synonym Gene Names
PSP-D; SP-D  [Similar Products]
UniProt Entry Name
SFTPD_PIG
UniProt Comments for SFTPD
Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties ().
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with anti-SFTPD antibody
Organs/Tissues associated with anti-SFTPD antibody
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >34 publications with SFTPD and Lung
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