• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-HSP90B1 antibody :: Rat Glucose-Regulated Protein 94 Monoclonal Antibody

Scan QR to view Datasheet
Catalog # MBS602720
Unit / Price
Scan QR to view Datasheet
  0.25 mL  /  $425 +1 FREE 8GB USB
  0.5 mL  /  $650 +1 FREE 8GB USB
anti-HSP90B1 antibody
Product Name

Glucose-Regulated Protein 94 (HSP90B1), Monoclonal Antibody

Full Product Name

Glucose-Regulated Protein 94

Product Synonym Names
Anti -Glucose-Regulated Protein 94
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 12; NC_000012.11 (104324189..104341703). Location: 12q24.2-q24.3
3D Structure
ModBase 3D Structure for P14625
Clone Number
Species Reactivity
Bovine, Canine, Chicken, Equine, Guinea Pig, Hamster, Human, Monkey, Mouse, Porcine, Rabbit, Rat, Sheep, Xenopus
Recognizes chicken glucose-regulated protein 94 (grp94) at 94kD. Species Crossreactivity: Human, monkey, equine, bovine, sheep, porcine, canine, rabbit, rat, mouse, hamster, guinea pig and Xenopus.
Affinity Purified
Purified by Protein G affinity chromatography.
Supplied as a liquid in 10mM PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide. Also available without BSA and azide. See G3057X.
Purified glucose regulated protein 94 (grp94) from chicken oviducts
Cellular Localization
Cytoplasmic and nuclear
Positive Control
SKBR-3 cells. Tonsil
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C or colder. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Other Notes
Small volumes of anti-HSP90B1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-HSP90B1 antibody
Grp's (Glucose-Regulated Proteins) are a class of proteins synthesized in cells in response to glucose starvation. Glucose-regulated protein 94 (grp94) or tumor rejection antigen (gp96) shows a high degree of sequence homology with the heat shock protein 90 (hsp90). Grp94 has been briefly studied as a prognostic factor in breast cancer.
Applications Tested/Suitable for anti-HSP90B1 antibody
Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
Application Notes for anti-HSP90B1 antibody
Suitable for use in Immunoprecipitation (native only), Western Blot and Immunohistochemistry.
Dilution: Immunoprecipitation: Use Protein G; 2ug/mg protein lysate
Western Blot: 1-2ug/ml for 2 hrs at RT.
NCBI/Uniprot data below describe general gene information for HSP90B1. It may not necessarily be applicable to this product.
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
92,469 Da[Similar Products]
NCBI Official Full Name
glucose regulated protein 94
NCBI Official Synonym Full Names
heat shock protein 90kDa beta (Grp94), member 1
NCBI Official Symbol
HSP90B1  [Similar Products]
NCBI Official Synonym Symbols
  [Similar Products]
NCBI Protein Information
endoplasmin; GRP-94; gp96 homolog; tumor rejection antigen 1; 94 kDa glucose-regulated protein; Tumor rejection antigen-1 (gp96); tumor rejection antigen (gp96) 1; glucose regulated protein, 94 kDa; endothelial cell (HBMEC) glycoprotein; heat shock protein 90 kDa beta member 1
UniProt Protein Name
UniProt Synonym Protein Names
94 kDa glucose-regulated protein; GRP-94; Heat shock protein 90 kDa beta member 1; Tumor rejection antigen 1; gp96 homolog
Protein Family
UniProt Gene Name
HSP90B1  [Similar Products]
UniProt Synonym Gene Names
GRP94; TRA1  [Similar Products]
UniProt Entry Name
NCBI Summary for HSP90B1
HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. HSP90B1 is an endoplasmic reticulum HSP90 protein. Other HSP90 proteins are found in cytosol (see HSP90AA1; MIM 140571) and mitochondria (TRAP1; MIM 606219) (Chen et al., 2005 [PubMed 16269234]).[supplied by OMIM]
UniProt Comments for HSP90B1
GRP94: Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. Homodimer; disulfide-linked. Component of an EIF2 complex at least composed of CELF1/CUGBP1, CALR, CALR3, EIF2S1, EIF2S2, HSP90B1 and HSPA5. Part a large chaperone multiprotein complex comprising DNAJB11, HSP90B1, HSPA5, HYOU, PDIA2, PDIA4, PDIA6, PPIB, SDF2L1, UGT1A1 and very small amounts of ERP29, but not, or at very low levels, CALR nor CANX. Interacts with AIMP1; regulates its retention in the endoplasmic reticulum. Interacts with OS9. Interacts with CNPY3. This interaction is disrupted in the presence of ATP. Interacts with TLR4 and TLR9, but not with TLR3. Belongs to the heat shock protein 90 family.

Protein type: Secreted; Apoptosis; Secreted, signal peptide; Heat shock protein

Chromosomal Location of Human Ortholog: 12q24.2-q24.3

Cellular Component: endoplasmic reticulum membrane; focal adhesion; endoplasmic reticulum lumen; endoplasmic reticulum; extracellular region; cytosol; extracellular matrix; membrane; perinuclear region of cytoplasm; melanosome; plasma membrane; midbody; nucleus

Molecular Function: protein binding; low-density lipoprotein receptor binding; RNA binding; unfolded protein binding; virion binding; calcium ion binding; protein phosphatase binding; ATP binding

Biological Process: actin rod formation; receptor-mediated endocytosis; ER-associated protein catabolic process; unfolded protein response; regulation of phosphoprotein phosphatase activity; protein transport; unfolded protein response, activation of signaling protein activity; cellular protein metabolic process; sequestering of calcium ion; response to hypoxia; toll-like receptor signaling pathway; innate immune response; negative regulation of apoptosis
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with anti-HSP90B1 antibody
 Reference Product  PubMed Publications
 TLR2 antibody  >1 publications with HSP90B1 and TLR2
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

Contact Us

Please fill out the form below and our representative will get back to you shortly.