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anti-a/b SNAP antibody :: Mouse a/b SNAP Monoclonal Antibody

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Catalog # MBS395170
Unit / Price
  0.1 mg  /  $340 +1 FREE 8GB USB
Western Blot/Blotting
Product Name

a/b SNAP, Monoclonal Antibody

Popular Item
Full Product Name

a/b SNAP

Product Synonym Names
alpha/beta SNAP; mouse anti alpha/beta soluble NSF attachment protein
Product Gene Name

anti-a/b SNAP antibody

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Chromosome Location
Chromosome: 19; NC_000019.9 (47990891..48018515, complement). Location: 19q13.33
OMIM
603215
3D Structure
ModBase 3D Structure for P54920
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
16D1
Host
Mouse
Species Reactivity
Human, Rat, Bovine, Chicken
Form/Format
20 mM sodium phosphate, 150 mM sodium chloride, 50% glycerol, pH 7.5
Immunogen
Recombinant human alpha SNAP
Positive Control
Rat brain
Preparation and Storage
Product should be stored at -20 degree C. Aliquot to avoid freeze/thaw cycles
Other Notes
Small volumes of anti-a/b SNAP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for
anti-a/b SNAP antibody
38 kDa SNAPs (soluble NSF attachment proteins), acting in concert with SNAREs (SNAP receptors) and the N-ethylmaleimide-
Product Categories/Family for anti-a/b SNAP antibody
Monoclonal Antibody; Neuronal Signaling
Applications Tested/Suitable for anti-a/b SNAP antibody
Western Blot (WB)
Western Blot/Blotting of anti-a/b SNAP antibody
Western blot (10% SDS-PAGE) of chicken brain (lane 1), chicken kidney (lane 2), rat brain (lane 3) and rat kidney (lane 4) probed with clone 16D1 anti- / SNAP at 0.2 g/ml.
anti-a/b SNAP antibody Western Blot/Blotting (WB) image
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NCBI/Uniprot data below describe general gene information for a/b SNAP. It may not necessarily be applicable to this product.
NCBI GI #
47933379
NCBI GeneID
8775
NCBI Accession #
NP_003818.2 [Other Products]
NCBI GenBank Nucleotide #
NM_003827.3 [Other Products]
UniProt Primary Accession #
P54920 [Other Products]
UniProt Secondary Accession #
Q96IK3; Q9BVJ3; A8K879[Other Products]
UniProt Related Accession #
P54920[Other Products]
Molecular Weight
38
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NCBI Official Full Name
alpha-soluble NSF attachment protein
NCBI Official Synonym Full Names
N-ethylmaleimide-sensitive factor attachment protein, alpha
NCBI Official Symbol
NAPA  [Similar Products]
NCBI Official Synonym Symbols
SNAPA
  [Similar Products]
NCBI Protein Information
alpha-soluble NSF attachment protein; alpha-SNAP
UniProt Protein Name
Alpha-soluble NSF attachment protein
UniProt Synonym Protein Names
N-ethylmaleimide-sensitive factor attachment protein alpha
UniProt Gene Name
NAPA  [Similar Products]
UniProt Synonym Gene Names
SNAPA; SNAP-alpha  [Similar Products]
UniProt Entry Name
SNAA_HUMAN
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NCBI Summary for a/b SNAP
This gene encodes a member of the soluble NSF attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. The encoded protein plays a role in the completion of membrane fusion by mediating the interaction of N-ethylmaleimide-sensitive factor (NSF) with the vesicle-associated and membrane-associated SNAP receptor (SNARE) complex, and stimulating the ATPase activity of NSF. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jun 2011]
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UniProt Comments for a/b SNAP
Function: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

Subunit structure: Interacts with PRKCABP, and disrupts the interaction between GRIA2 and PRKCABP, leading to the internalization of GRIA2. Found in a complex with VAMP8

By similarity. Component of a SNARE-like complex that contains at least ZW10, USE1L, RINT1, STX18 and NAPA/SNAP-alpha. Interacts with VTI1A. Interacts with STX12

By similarity. Ref.7

Subcellular location: Membrane; Peripheral membrane protein.

Sequence similarities: Belongs to the SNAP family.
Research Articles on a/b SNAP
1. Study revealed a novel role for alphaSNAP as a negative regulator of autophagy that acts by enhancing mTOR signaling and regulating the integrity of the Golgi complex.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated withanti-a/b SNAP antibody
 Reference Product  PubMed Publications
 NSF antibody  >2 publications with a/b SNAP and NSF
 SNAP25 antibody  >1 publications with a/b SNAP and SNAP25
 VAMP2 antibody  >1 publications with a/b SNAP and VAMP2
 STX1A antibody  >1 publications with a/b SNAP and STX1A
Pathways associated with anti-a/b SNAP antibody
 Products by Pathway  Pathway Diagram
 Clathrin Derived Vesicle Budding Pathway antibodies  Clathrin Derived Vesicle Budding Pathway Diagram
 Golgi Associated Vesicle Biogenesis Pathway antibodies  Golgi Associated Vesicle Biogenesis Pathway Diagram
 Membrane Trafficking Pathway antibodies  Membrane Trafficking Pathway Diagram
 Synaptic Vesicle Pathway antibodies  Synaptic Vesicle Pathway Diagram
 Synaptic Vesicle Cycle Pathway antibodies  Synaptic Vesicle Cycle Pathway Diagram
 Synaptic Vesicle Cycle Pathway antibodies  Synaptic Vesicle Cycle Pathway Diagram
 Trans-Golgi Network Vesicle Budding Pathway antibodies  Trans-Golgi Network Vesicle Budding Pathway Diagram
Diseases associated with anti-a/b SNAP antibody
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >61 publications with a/b SNAP and Cardiovascular Diseases
 Nervous System Diseases Antibodies  >43 publications with a/b SNAP and Nervous System Diseases
 Neoplasms Antibodies  >39 publications with a/b SNAP and Neoplasms
 Drug Toxicity Antibodies  >30 publications with a/b SNAP and Drug Toxicity
 Poisoning Antibodies  >20 publications with a/b SNAP and Poisoning
 Kidney Diseases Antibodies  >18 publications with a/b SNAP and Kidney Diseases
 Breast Neoplasms Antibodies  >14 publications with a/b SNAP and Breast Neoplasms
 Inflammation Antibodies  >10 publications with a/b SNAP and Inflammation
 Adenocarcinoma Antibodies  >9 publications with a/b SNAP and Adenocarcinoma
 Disease Models, Animal Antibodies  >8 publications with a/b SNAP and Disease Models, Animal
Organs/Tissues associated with anti-a/b SNAP antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >134 publications with a/b SNAP and Blood
 Heart Antibodies  >61 publications with a/b SNAP and Heart
 Kidney Antibodies  >44 publications with a/b SNAP and Kidney
 Brain Antibodies  >34 publications with a/b SNAP and Brain
 Liver Antibodies  >25 publications with a/b SNAP and Liver
 Muscle Antibodies  >19 publications with a/b SNAP and Muscle
 Vascular Antibodies  >14 publications with a/b SNAP and Vascular
 Nerve Antibodies  >10 publications with a/b SNAP and Nerve
 Skin Antibodies  >9 publications with a/b SNAP and Skin
 Bone Antibodies  >8 publications with a/b SNAP and Bone
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