NP_003818.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
alpha-soluble NSF attachment protein
NCBI Official Synonym Full Names
N-ethylmaleimide-sensitive factor attachment protein, alpha
NCBI Official Synonym Symbols
NCBI Protein Information
alpha-soluble NSF attachment protein; alpha-SNAP
UniProt Protein Name
Alpha-soluble NSF attachment protein
UniProt Synonym Protein Names
N-ethylmaleimide-sensitive factor attachment protein alpha
UniProt Synonym Gene Names
UniProt Entry Name
SNAA_HUMAN
NCBI Summary for a/b SNAP
This gene encodes a member of the soluble NSF attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. The encoded protein plays a role in the completion of membrane fusion by mediating the interaction of N-ethylmaleimide-sensitive factor (NSF) with the vesicle-associated and membrane-associated SNAP receptor (SNARE) complex, and stimulating the ATPase activity of NSF. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jun 2011]
UniProt Comments for a/b SNAP
Function: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.
Subunit structure: Interacts with PRKCABP, and disrupts the interaction between GRIA2 and PRKCABP, leading to the internalization of GRIA2. Found in a complex with VAMP8
By similarity. Component of a SNARE-like complex that contains at least ZW10, USE1L, RINT1, STX18 and NAPA/SNAP-alpha. Interacts with VTI1A. Interacts with STX12
By similarity. Ref.7
Subcellular location: Membrane; Peripheral membrane protein.
Sequence similarities: Belongs to the SNAP family.
Research Articles on a/b SNAP
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Products associated withanti-a/b SNAP antibody
Pathways associated with anti-a/b SNAP antibody
Diseases associated with anti-a/b SNAP antibody
Organs/Tissues associated with anti-a/b SNAP antibody
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