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anti-NCAM antibody :: Mouse NCAM / CD56 Monoclonal Antibody

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Catalog # MBS245133
Unit / Price
  0.05 mg  /  $530 +1 FREE 8GB USB
Product Name

NCAM / CD56, Monoclonal Antibody

Also Known As

Mouse Monoclonal [clone MEM-188] (IgG2a) to Human NCAM / CD56

Product Synonym Names
Anti-NCAM / CD56 Antibody (clone MEM-188) IHC-plus; NCAM1; CD56; CD56 antigen; MSK39; NCAM-1; N-CAM-1; NCAM; Human NCAM; CD56
Product Synonym Gene Name
CD56; NCAM1[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
848
OMIM
116930
3D Structure
ModBase 3D Structure for P13591
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
MEM-188
Host
Mouse
Species Reactivity
Bovine, Human, Pig
Specificity
KG-1 human acute myelogenous leukemia cell line
Purity/Purification
Affinity Purified
Form/Format
Phosphate-buffered solution, pH 7.2, 0.09% sodium azide.
Concentration
0.5 mg/ml (lot specific)
Target Species
Human
Immunogen Description
Cells.
Immunogen
NCAM / CD56 antibody was raised against cells.
Preparation and Storage
Store at 4 degree C.
Other Notes
Small volumes of anti-NCAM antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-NCAM antibody
Applications Tested/Suitable for anti-NCAM antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
Application Notes for anti-NCAM antibody
Flo, IHC-P (10 ug/ml), IP, WB
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-NCAM antibody
Anti-CD56 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
anti-NCAM antibody Immunohistochemistry (IHC) (IHC) image
Flow Cytometry (FC/FACS) of anti-NCAM antibody
Human peripheral blood lymphocytes stained with purified MEM-188, followed by anti-mouse IgGs FITC
anti-NCAM antibody Flow Cytometry (FC/FACS) (FC/FACS) image
NCBI/Uniprot data below describe general gene information for NCAM. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
40,760 Da
NCBI Official Full Name
neural cell adhesion molecule 1 isoform 1
NCBI Official Synonym Full Names
neural cell adhesion molecule 1
NCBI Official Symbol
NCAM1  [Similar Products]
NCBI Official Synonym Symbols
CD56; NCAM; MSK39
  [Similar Products]
NCBI Protein Information
neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM; antigen recognized by monoclonal antibody 5.1H11
UniProt Protein Name
Neural cell adhesion molecule 1
UniProt Synonym Protein Names
CD_antigen: CD56
UniProt Gene Name
NCAM1  [Similar Products]
UniProt Synonym Gene Names
NCAM; N-CAM-1; NCAM-1  [Similar Products]
UniProt Entry Name
NCAM1_HUMAN
NCBI Summary for NCAM
This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]
UniProt Comments for NCAM
NCAM1: This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Membrane protein, GPI anchor; Cell adhesion

Chromosomal Location of Human Ortholog: 11q23.1

Cellular Component: Golgi membrane; cell surface; membrane; integral to membrane; plasma membrane; external side of plasma membrane

Molecular Function: identical protein binding

Biological Process: axon guidance; extracellular matrix organization and biogenesis; cytokine and chemokine mediated signaling pathway; cell adhesion
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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