NP_000606.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
neural cell adhesion molecule 1 isoform 1
NCBI Official Synonym Full Names
neural cell adhesion molecule 1
NCBI Protein Information
neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM; antigen recognized by monoclonal antibody 5.1H11
UniProt Protein Name
Neural cell adhesion molecule 1
UniProt Synonym Protein Names
CD_antigen: CD56
UniProt Synonym Gene Names
UniProt Entry Name
NCAM1_HUMAN
NCBI Summary for NCAM
This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]
UniProt Comments for NCAM
NCAM1: This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. 6 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Membrane protein, GPI anchor; Cell adhesion
Chromosomal Location of Human Ortholog: 11q23.1
Cellular Component: Golgi membrane; cell surface; membrane; integral to membrane; plasma membrane; external side of plasma membrane
Molecular Function: identical protein binding
Biological Process: axon guidance; extracellular matrix organization and biogenesis; cytokine and chemokine mediated signaling pathway; cell adhesion
Research Articles on NCAM
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Pathways associated with anti-NCAM antibody
Diseases associated with anti-NCAM antibody
Organs/Tissues associated with anti-NCAM antibody
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