• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-PP2A alpha antibody :: Mouse PP2A alpha Monoclonal Antibody

Scan QR to view Datasheet
Catalog # MBS375097
Unit / Price
Scan QR to view Datasheet
  0.1 mL  /  $415 +1 FREE 8GB USB
anti-PP2A alpha antibody
Product Name

PP2A alpha, Monoclonal Antibody

Popular Item
Full Product Name

Mouse Anti-PP2A alpha (methyl L309) [2A10]

Product Synonym Names
PP2A alpha antibody; PP2A C antibody; PP2A-alpha antibody; PP2AA_HUMAN antibody; PP2Ac antibody; PP2CA antibody; PPP2CA antibody; Protein phosphatase 2, catalytic subunit, alpha isoform antibody; Replication protein C antibody
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2A10
Host
Mouse
Species Reactivity
Mouse, Human, Saccharomyces cerevisiae
Specificity
Alpha + beta isoforms of PP2A C
Purity/Purification
Protein G
Form/Format
Purified antibody (from supernatant) containing PBS + 0.1% sodium azide
Concentration
1mg/ml (lot specific)
Target Antigen
PP2A alpha (methyl L309)
Immunogen
C-terminal peptide (Methyl-Leu309) of human PP2A catalic subunit.
Myeloma/fusion Partners
X63-Ag8.653
Health & Safty
Products that contain sodium azide (a poisonous and hazardous substance) should be handled by trained staffs only.
Preparation and Storage
Store at 4 degree C for one month, or in small aliquots at -20 degree C for longer periods. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody.
Other Notes
Small volumes of anti-PP2A alpha antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-PP2A alpha antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes for anti-PP2A alpha antibody
Optimal antibody dilution should be determined by titration, however as a guideline start at 1:500 for Wester Blot.
Product References and Citations for anti-PP2A alpha antibody
Benziane B et al. Activation of AMP-activated Protein Kinase Stimulates Na+,K+-ATPase Activity in Skeletal Muscle Cells. J Biol Chem 287:23451-63 (2012). WB PUBMED Li T et al. Microcystin-LR (MCLR) Induces a Compensation of PP2A Activity Mediated by a4 Protein in HEK293 Cells. Int J Biol Sci 7:740-52 (2011). WB ; Human PUBMED Finnegan S et al. A stress survival response in retinal cells mediated through inhibition of the serine / threonine phosphatase PP2A. Eur J Neurosci : (2010). WB ; Mouse PUBMED Hombauer H et al. Generation of active protein phosphatase 2A is coupled to holoenzyme assembly. PLoS Biol 5:e155 (2007) PUBMED Sontag E et al. Downregulation of protein phosphatase 2A carboxyl methylation and methyltransferase may contribute to Alzheimer disease pathogenesis. J Neuropathol Exp Neurol 63:1080-91 (2004) PUBMED Sontag E et al. Altered expression levels of the protein phosphatase 2A ABalphaC enzyme are associated with Alzheimer disease pathology. J Neuropathol Exp Neurol 63:287-301 (2004) PUBMED Fellner T et al. A novel and essential mechanism determining specificity and activity of protein phosphatase 2A (PP2A) in vivo. Genes Dev 17:2138-50 (2003) PUBMED

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000