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anti-PP2A alpha antibody :: Mouse PP2A alpha Monoclonal Antibody

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Catalog # MBS375097
Unit / Price
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  0.1 mL  /  $415 +1 FREE 8GB USB
anti-PP2A alpha antibody
Product Name

PP2A alpha, Monoclonal Antibody

Popular Item
Full Product Name

Mouse Anti-PP2A alpha (methyl L309) [2A10]

Product Synonym Names
PP2A alpha antibody; PP2A C antibody; PP2A-alpha antibody; PP2AA_HUMAN antibody; PP2Ac antibody; PP2CA antibody; PPP2CA antibody; Protein phosphatase 2, catalytic subunit, alpha isoform antibody; Replication protein C antibody
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Clone Number
Species Reactivity
Mouse, Human, Saccharomyces cerevisiae
Alpha + beta isoforms of PP2A C
Protein G
Purified antibody (from supernatant) containing PBS + 0.1% sodium azide
1mg/ml (lot specific)
Target Antigen
PP2A alpha (methyl L309)
C-terminal peptide (Methyl-Leu309) of human PP2A catalic subunit.
Myeloma/fusion Partners
Health & Safty
Products that contain sodium azide (a poisonous and hazardous substance) should be handled by trained staffs only.
Preparation and Storage
Store at 4 degree C for one month, or in small aliquots at -20 degree C for longer periods. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody.
Other Notes
Small volumes of anti-PP2A alpha antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-PP2A alpha antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes for anti-PP2A alpha antibody
Optimal antibody dilution should be determined by titration, however as a guideline start at 1:500 for Wester Blot.
Product References and Citations for anti-PP2A alpha antibody
Benziane B et al. Activation of AMP-activated Protein Kinase Stimulates Na+,K+-ATPase Activity in Skeletal Muscle Cells. J Biol Chem 287:23451-63 (2012). WB PUBMED Li T et al. Microcystin-LR (MCLR) Induces a Compensation of PP2A Activity Mediated by a4 Protein in HEK293 Cells. Int J Biol Sci 7:740-52 (2011). WB ; Human PUBMED Finnegan S et al. A stress survival response in retinal cells mediated through inhibition of the serine / threonine phosphatase PP2A. Eur J Neurosci : (2010). WB ; Mouse PUBMED Hombauer H et al. Generation of active protein phosphatase 2A is coupled to holoenzyme assembly. PLoS Biol 5:e155 (2007) PUBMED Sontag E et al. Downregulation of protein phosphatase 2A carboxyl methylation and methyltransferase may contribute to Alzheimer disease pathogenesis. J Neuropathol Exp Neurol 63:1080-91 (2004) PUBMED Sontag E et al. Altered expression levels of the protein phosphatase 2A ABalphaC enzyme are associated with Alzheimer disease pathology. J Neuropathol Exp Neurol 63:287-301 (2004) PUBMED Fellner T et al. A novel and essential mechanism determining specificity and activity of protein phosphatase 2A (PP2A) in vivo. Genes Dev 17:2138-50 (2003) PUBMED

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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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