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anti-TUBB antibody :: beta-Tubulin Monoclonal Antibody

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Catalog # MBS475115
Unit / Price
  0.1 mL  /  $335 +1 FREE 8GB USB
Product Name

beta-Tubulin (TUBB), Monoclonal Antibody

Popular Item
Also Known As

Anti-beta-Tubulin Mouse mAb

Product Synonym Names
beta 4 tubulin; Beta 5 tubulin; beta Ib tubulin; M40; TUBB1; TUBB5; tubulin beta 1 chain; Tubulin beta 4 chain; tubulin beta 5 chain; Tubulin beta; Tubulin beta chain; tubulin beta polypeptide
Product Synonym Gene Name
M40; TUBB1; TUBB5; OK/SW-cl.56[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
464
OMIM
J00314 Genomic DNA
3D Structure
ModBase 3D Structure for P07437
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1E1-E8-H4
Host
Mouse
Source: Human
Species Reactivity
Human, Mouse, Monkey, Goat, Hamster, Rat, Chlamydomonas
Purity/Purification
Affinity Purified
Form/Format
Purified mouse monoclonal in PBS (pH 7.4) containing with 0.02% sodium azide, 0.1mg/mlBSA and 50% glycerol.
Concentration
1mg/ml (lot specific)
Immunogen
Purified recombinant human Tubulin beta protein fragments expressed in E Coli.
Sensitivity
This antibody detects endogenous levels of Tubulin beta and does not cross-react with related proteins.
Sequence Similarities
Belongs to the tubulin family.
Subunit Structure
Dimer of alpha and beta chains.May interact with RNABP10 By similarity.Interacts with PIFO.Interacts with MX1.
Subcellular Location
Cytoplasm; cytoskeleton.
Other Notes
Small volumes of anti-TUBB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-TUBB antibody
UniPort Summary Function: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.
Applications Tested/Suitable for anti-TUBB antibody
Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-TUBB antibody
WB: 1:5000
ICC: 1:500

Western Blot (WB) of anti-TUBB antibody
Western blot detection of Tubulin beta in COS7, LNCap, MCF7 and C2C12 cell lysates and using Tubulin beta mouse mAb (1:5000 diluted).Predicted band size: 55KDa.Observed band size: 55KDa.
anti-TUBB antibody Western Blot (WB) (WB) image
Immunocytochemistry (ICC) of anti-TUBB antibody
Immunocytochemistry staining of HeLa cells fixed with 4% paraformaldehyde and using anti-Tubulin beta mouse mAb (dilution 1:500).
anti-TUBB antibody Immunocytochemistry (ICC) (ICC) image
Testing Data of anti-TUBB antibody
Tubulin beta antibody's stability test under 37 degree C 50 hours compare to 4 degree C 50 hours.
anti-TUBB antibody Testing Data image
Western Blot (WB) of anti-TUBB antibody
Western blot detection of Tubulin beta in goat intestine, goat skeletal muscle, goat spleen and goat lung cell lysates using Tubulin beta mouse mAb (1:5000-1:10000 diluted).Predicted band size: 55KDa.Observed band size: 55KDa.
anti-TUBB antibody Western Blot (WB) (WB) image
Western Blot (WB) of anti-TUBB antibody
Western blot detection of Tubulin beta in Goat skeletal muscle, CHO-k1, COS7, C6, 3T3 and K562 cell lysates using Tubulin beta mouse mAb (1:5000 diluted).Predicted band size:55KDa.Observed band size:55KDa.Exposure time:10sec.
anti-TUBB antibody Western Blot (WB) (WB) image
Western Blot (WB) of anti-TUBB antibody
Western blot detection of beta Tubulin in Chlamydomonas cell lysates using beta Tubulin mouse mAb (1:1000 diluted).Predicted band size:55KDa.Observed band size:55KDa.
anti-TUBB antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for TUBB. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
55
NCBI Official Full Name
tubulin beta chain isoform a
NCBI Official Synonym Full Names
tubulin beta class I
NCBI Official Symbol
NCBI Official Synonym Symbols
M40; TUBB1; TUBB5; CDCBM6; CSCSC1; OK/SW-cl.56
  [Similar Products]
NCBI Protein Information
tubulin beta chain
UniProt Protein Name
Tubulin beta chain
UniProt Synonym Protein Names
Tubulin beta-5 chain
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
TUBB5  [Similar Products]
NCBI Summary for TUBB
This gene encodes a beta tubulin protein. This protein forms a dimer with alpha tubulin and acts as a structural component of microtubules. Mutations in this gene cause cortical dysplasia, complex, with other brain malformations 6. Alternative splicing results in multiple splice variants. There are multiple pseudogenes for this gene on chromosomes 1, 6, 7, 8, 9, and 13. [provided by RefSeq, Jun 2014]
UniProt Comments for TUBB
TUBB: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. Dimer of alpha and beta chains. May interact with RNABP10. Interacts with PIFO/C1orf88. Ubiquitously expressed with highest levels in spleen, thymus and immature brain. Belongs to the tubulin family.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 6p21.33

Cellular Component: cytoskeleton; extracellular matrix; extracellular region; microtubule; nuclear envelope lumen; nucleus

Molecular Function: MHC class I protein binding; protein binding; structural molecule activity; ubiquitin protein ligase binding

Biological Process: cell division; cell motility; cellular process; cytoskeleton-dependent intracellular transport; G2/M transition of mitotic cell cycle; microtubule-based process

Disease: Cortical Dysplasia, Complex, With Other Brain Malformations 6; Skin Creases, Congenital Symmetric Circumferential, 1
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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