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anti-ABCC4 antibody :: Mouse anti-Human ABCC4 Monoclonal Antibody

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Catalog # MBS476437
Unit / Price
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  0.1 mL  /  $335 +1 FREE 8GB USB
Product Name

ABCC4, Monoclonal Antibody

Full Product Name

Anti-ABCC4 Mouse mAb

Product Synonym Names
MRP4; MOATB; MOAT-B; EST170205
Product Synonym Gene Name
MRP4; MOATB; MOAT-B; EST170205[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
AF071202 mRNA
Clonality
Monoclonal
Isotype
IgG1
Clone Number
6A7H3
Host
Mouse
Species Reactivity
Human
Form/Format
Purified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer
Immunogen
Purified recombinant fragment of human ABCC4 (AA: 631-692) expressed in E Coli.
Other Notes
Small volumes of anti-ABCC4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ABCC4 antibody
Entrez Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms.
Applications Tested/Suitable for anti-ABCC4 antibody
Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)

Western Blot (WB) of anti-ABCC4 antibody
Western blot analysis using ABCC4 mAb against human ABCC4 recombinant protein. (Expected MW is 32.4 kDa)
anti-ABCC4 antibody Western Blot (WB) (WB) image
Western Blot (WB) of anti-ABCC4 antibody
Western blot analysis using ABCC4 mAb against HEK293 (1) and ABCC4 (AA
anti-ABCC4 antibody Western Blot (WB) (WB) image
Flow Cytometry (FC/FACS) of anti-ABCC4 antibody
Flow cytometric analysis of A549 cells using ABCC4 mouse mAb (green) and negative control (red).
anti-ABCC4 antibody Flow Cytometry (FC/FACS) (FC/FACS) image
Immunohistochemistry (IHC) of anti-ABCC4 antibody
Immunohistochemical analysis of paraffin-embedded liver cancer tissues using ABCC4 mouse mAb with DAB staining.
anti-ABCC4 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-ABCC4 antibody
Immunohistochemical analysis of paraffin-embedded esophagus cancer tissues using ABCC4 mouse mAb with DAB staining.
anti-ABCC4 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for ABCC4. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
150
NCBI Official Full Name
ABCC4 protein
NCBI Official Synonym Full Names
ATP binding cassette subfamily C member 4
NCBI Official Symbol
ABCC4  [Similar Products]
NCBI Official Synonym Symbols
MRP4; MOATB; MOAT-B
  [Similar Products]
NCBI Protein Information
multidrug resistance-associated protein 4
UniProt Protein Name
Multidrug resistance-associated protein 4
UniProt Synonym Protein Names
ATP-binding cassette sub-family C member 4; MRP/cMOAT-related ABC transporter; Multi-specific organic anion transporter B; MOAT-B
Protein Family
UniProt Gene Name
ABCC4  [Similar Products]
UniProt Synonym Gene Names
MRP4; MOAT-B  [Similar Products]
NCBI Summary for ABCC4
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This family member plays a role in cellular detoxification as a pump for its substrate, organic anions. It may also function in prostaglandin-mediated cAMP signaling in ciliogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
UniProt Comments for ABCC4
ABCC4: a widely-expressed multi-pass membrane protein. An organic anion pump involved in cellular detoxification. Widely expressed, with particularly high levels in prostate, but is barely detectable in liver.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, ABC family

Chromosomal Location of Human Ortholog: 13q32.1

Cellular Component: basolateral plasma membrane; membrane; plasma membrane; platelet dense granule membrane

Molecular Function: anion transmembrane-transporting ATPase activity; ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism

Biological Process: platelet degranulation; prostaglandin secretion; transmembrane transport
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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