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Mouse anti-Human amyloid beta peptide N-terminal Monoclonal Antibody

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Catalog # MBS592372
Unit / Price
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  0.5 mg  /  $445 +1 FREE 8GB USB
anti-amyloid beta peptide N-terminal antibody
Product Name

amyloid beta peptide N-terminal, Monoclonal Antibody

Popular Item
Full Product Name

mAb anti-human amyloid beta peptide N-terminal

Product Synonym Names
Beta amyloid peptide N-terminal; Mouse monoclonal antibody against N-terminal sequence of human amyloid beta peptides
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
NT 4A2
Host
Mouse
Species Reactivity
Human
Specificity
This antibody recognizes the N-terminal peptide (DAEFRHDS) of human beta amyloid peptides and also reacts with full length Abeta40, Abeta42 and Abeta43.
Beta amyloid peptide N-terminal
Purity/Purification
Protein G affinity purified
Form/Format
Lyophilized from a solution in 0.01M PBS pH7.2
Target Protein
Human beta amyloid peptide 42
Immunogen
Full length human beta amyloid peptide 42
Myeloma
Sp2/0-Ag14
Light Chain
Kappa
Reconstitution
Double distilled water is recommended to adjust the final concentration to 1.00 mg/mL.
Research Area
Aging and neurodegenerative diseases
Preparation and Storage
Store at -20 degree C
Other Notes
Small volumes of anti-amyloid beta peptide N-terminal antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-amyloid beta peptide N-terminal antibody
Description: Mouse monoclonal antibody against N-terminal sequence of human amyloid beta peptides

background: Abeta40, Abeta42 and Abeta43 are different only at the few C-end amino acids. While the C-end amino acids showed no species-specificity in mammalians, the N-terminal amino acid sequences have minor discrepancies between difference species.
Amyloid beta peptides Abeta42 and Abeta40 have been investigated extensively for predicating Alzheimer's disease. A recent study on A Abeta43 in brain showed that Abeta43 is more fibrillogenic than the other amyloid beta peptides and may be useful as a biomarker or therapeutic target for Alzheimer's disease. Antibody to N-terminal sequence can bind to all the three amyloid beta peptides.
Applications Tested/Suitable for anti-amyloid beta peptide N-terminal antibody
ELISA (EIA)
ELISA: The antibody can be used as capture antibody in Sandwich ELISA for Abeta42 detection in combination with detection antibody CA9 10C11.
The antibody can be used as capture antibody in Sandwich ELISA for Abeta40 detection in combination with detection antibody CV9 7B11
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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