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anti-BSG antibody :: Mouse anti-Human Basigin / Emmprin / CD147 Monoclonal Antibody

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Catalog # MBS245487
Unit / Price
  0.05 mg  /  $530 +1 FREE 8GB USB
Product Name

Basigin / Emmprin / CD147 (BSG), Monoclonal Antibody

Also Known As

Mouse Monoclonal [clone MEM-M6/1] (IgG1) to Human Basigin / Emmprin / CD147

Product Synonym Names
Anti-Basigin / Emmprin / CD147 Antibody (clone MEM-M6/1) IHC-plus; BSG; 5F7; Basigin; Basigin (Ok blood group); CD147 antigen; Collagenase stimulatory factor; EMMPRIN; OK; OK blood group antigen; TCSF; CD147; M6; Emmprin; Human Basigin; Emmprin; CD147
Product Gene Name
Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
385
OMIM
gene 111380
3D Structure
ModBase 3D Structure for P35613
Clonality
Monoclonal
Isotype
IgG1
Clone Number
MEM-M6/1
Host
Mouse
Species Reactivity
Human
Purity/Purification
Protein G Purified
Form/Format
PBS, pH 7.4, 0.09% sodium azide.
Concentration
1 mg/ml (lot specific)
Target Species
Human
Immunogen Description
recombinant CD147Rg consisting of the cDNA coding for the hinge region CH2 and CH3 domain of human IgG1.
Immunogen Type
Recombinant protein
Immunogen
Basigin / Emmprin / CD147 antibody was raised against recombinant CD147Rg consisting of the cDNA coding for the hinge region CH2 and CH3 domain of human IgG1.
Preparation and Storage
+4 degree C or -20 degree C, Avoid repeated freezing and thawing.
Other Notes
Small volumes of anti-BSG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-BSG antibody
CD147 (BSG) is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. The encoded protein is also a member of the immunoglobulin superfamily. Multiple transcript variants encoding different isoforms have been found for this gene.
Applications Tested/Suitable for anti-BSG antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
Application Notes for anti-BSG antibody
Flo (1:50 - 1:100), IHC-P (10 ug/ml), IP, WB
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-BSG antibody
Anti-CD147 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
anti-BSG antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-BSG antibody
Anti-CD147 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
anti-BSG antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-BSG antibody
Anti-CD147 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
anti-BSG antibody Immunohistochemistry (IHC) (IHC) image
Flow Cytometry (FC/FACS) of anti-BSG antibody
Staining of red blood cells
anti-BSG antibody Flow Cytometry (FC/FACS) (FC/FACS) image
NCBI/Uniprot data below describe general gene information for BSG. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
22,764 Da
NCBI Official Full Name
basigin isoform 1
NCBI Official Synonym Full Names
basigin (Ok blood group)
NCBI Official Symbol
NCBI Official Synonym Symbols
M6; OK; 5F7; TCSF; CD147; EMMPRIN
  [Similar Products]
NCBI Protein Information
basigin; CD147 antigen; OK blood group antigen; collagenase stimulatory factor; leukocyte activation antigen M6; extracellular matrix metalloproteinase inducer; tumor cell-derived collagenase stimulatory factor
UniProt Protein Name
Basigin
UniProt Synonym Protein Names
5F7; Collagenase stimulatory factor; Extracellular matrix metalloproteinase inducer; EMMPRIN; Leukocyte activation antigen M6; OK blood group antigen; Tumor cell-derived collagenase stimulatory factor; TCSF; CD_antigen: CD147
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
EMMPRIN; TCSF  [Similar Products]
UniProt Entry Name
BASI_HUMAN
NCBI Summary for BSG
The protein encoded by this gene is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. The encoded protein is also a member of the immunoglobulin superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for BSG
BSG: Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). May target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes. Enriched on the surface of tumor cells. Up-regulated in gliomas. Its expression levels correlate with malignant potential of the tumor. Forms homooligomers in a cis-dependent manner on the plasma membrane. Forms a complex with MMP1 at the tumor cell surface. Interacts with SLC16A1 and SLC1A3; probably a BSG dimer is associated with a monocarboxylate transporter dimer. Interacts with ATP1B2, MAG and L1CAM. Interacts with AJAP1. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Immunoglobulin superfamily

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: Golgi membrane; focal adhesion; mitochondrion; membrane; integral to plasma membrane; melanosome; plasma membrane; sarcolemma; acrosomal membrane; lipid raft

Molecular Function: mannose binding; protein binding

Biological Process: response to peptide hormone stimulus; extracellular matrix organization and biogenesis; response to cAMP; decidualization; odontogenesis of dentine-containing teeth; response to mercury ion; cellular metabolic process; extracellular matrix disassembly; cell surface receptor linked signal transduction; blood coagulation; pyruvate metabolic process; leukocyte migration; embryo implantation

Disease: Blood Group--ok
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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