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anti-BRRN1 antibody :: Mouse anti-Human BRRN1 Monoclonal Antibody

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Catalog # MBS120479
Unit / Price
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  0.1 mg  /  $395 +1 FREE 8GB USB
Product Name

BRRN1, Monoclonal Antibody

Full Product Name

Mouse monoclonal antibody Anti-Human BRRN1

Product Synonym Names
Homo sapiens non-SMC condensin I complex, subunit H (NCAPH), mRNA.; BRRN1; CAP-H; HCAP-H
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
602332
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2094C4_2a
Host
Mouse
Species Reactivity
Human
Concentration
100 ug/ml (1.0 ml) (lot specific)
Preparation
This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Sterility
Filtered through a 0.22 um membrane.
Other Notes
Small volumes of anti-BRRN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-BRRN1 antibody
This gene encodes a member of the barr gene family and a regulatory subunit of the condensin complex. This complex is required for the conversion of interphase chromatin into condensed chromosomes. The protein encoded by this gene is associated with mitotic chromosomes, except during the early phase of chromosome condensation. During interphase, the protein has a distinct punctate nucleolar localization. [provided by RefSeq][NCBI Entrez Gene Summary]
Applications Tested/Suitable for anti-BRRN1 antibody
Dot Blot (DB)

Quality Control of anti-BRRN1 antibody
Western blot analysis of immunized recombinant protein, using anti-BRRN1 monoclonal antibody.
anti-BRRN1 antibody Quality Control image
Quality Control #2 of anti-BRRN1 antibody
Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.
anti-BRRN1 antibody Quality Control #2 image
NCBI/Uniprot data below describe general gene information for BRRN1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
67,495 Da
NCBI Official Full Name
Homo sapiens non-SMC condensin I complex, subunit H (NCAPH), transcript variant 1, mRNA
NCBI Official Synonym Full Names
non-SMC condensin I complex, subunit H
NCBI Official Symbol
NCAPH  [Similar Products]
NCBI Official Synonym Symbols
BRRN1; CAP-H
  [Similar Products]
NCBI Protein Information
condensin complex subunit 2; barren homolog 1; chromosome-associated protein H
UniProt Protein Name
Condensin complex subunit 2
UniProt Synonym Protein Names
Barren homolog protein 1; Chromosome-associated protein H; hCAP-H; Non-SMC condensin I complex subunit H; XCAP-H homolog
UniProt Gene Name
NCAPH  [Similar Products]
UniProt Entry Name
CND2_HUMAN
NCBI Summary for BRRN1
This gene encodes a member of the barr gene family and a regulatory subunit of the condensin complex. This complex is required for the conversion of interphase chromatin into condensed chromosomes. The protein encoded by this gene is associated with mitotic chromosomes, except during the early phase of chromosome condensation. During interphase, the protein has a distinct punctate nucleolar localization. Alternatively spliced transcript variants encoding different proteins have been described. [provided by RefSeq, Jul 2013]
UniProt Comments for BRRN1
NCAPH: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. Belongs to the CND2 (condensin subunit 2) family.

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: 2q11.2

Cellular Component: membrane; cytoplasm; condensin complex; nucleus; cytosol

Molecular Function: protein binding

Biological Process: cell division; mitotic chromosome condensation; mitotic cell cycle
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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