NP_003963.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
76,419 Da
NCBI Official Full Name
Homo sapiens BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa (BTAF1), mRNA
NCBI Official Synonym Full Names
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa
NCBI Official Synonym Symbols
MOT1; TAF172; TAFII170; TAF(II)170 [Similar Products]
NCBI Protein Information
TATA-binding protein-associated factor 172; ATP-dependent helicase BTAF1; B-TFIID transcription factor-associated 170 kDa subunit; BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa (Mot1 homolog, S. cerevisiae); TBP-associated factor 172
UniProt Protein Name
TATA-binding protein-associated factor 172
UniProt Synonym Protein Names
ATP-dependent helicase BTAF1; B-TFIID transcription factor-associated 170 kDa subunit; TAF(II)170; TBP-associated factor 172; TAF-172
UniProt Entry Name
BTAF1_HUMAN
NCBI Summary for BTAF1
This gene encodes a TAF (TATA box-binding protein-associated factor), which associates with TBP (TATA box-binding protein) to form the B-TFIID complex that is required for transcription initiation of genes by RNA polymerase II. This TAF has DNA-dependent ATPase activity, which drives the dissociation of TBP from DNA, freeing the TBP to associate with other TATA boxes or TATA-less promoters. [provided by RefSeq, Sep 2011]
UniProt Comments for BTAF1
TAF172: Regulates transcription in association with TATA binding protein (TBP). Removes TBP from the TATA box in an ATP-dependent manner. Associates with TBP to form B-TFIID. Binds DRAP1. Belongs to the SNF2/RAD54 helicase family.
Protein type: Helicase; EC 3.6.4.-; EC 3.6.1.-; Transcription initiation complex
Chromosomal Location of Human Ortholog: 10q22-q23
Cellular Component: nucleus
Molecular Function: DNA binding; helicase activity; transcription factor activity; ATP binding
Biological Process: metabolic process; negative regulation of transcription, DNA-dependent
Research Articles on BTAF1
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Products associated with anti-BTAF1 antibody
Diseases associated with anti-BTAF1 antibody
Organs/Tissues associated with anti-BTAF1 antibody
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