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anti-CD19 antibody :: Mouse anti-Human CD19 CD19 Monoclonal Antibody

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Catalog # MBS530888
Unit / Price
  0.5 mg  /  $570 +1 FREE 8GB USB
anti-CD19 antibody
Product Name

CD19, Monoclonal Antibody

Popular Item
Also Known As

CD19 antibody (Azide Free)

Product Synonym Names
Monoclonal CD19; Anti-CD19; CD 19; CD-19; CD19
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
556
OMIM
107265
3D Structure
ModBase 3D Structure for P15391
Clonality
Monoclonal
Isotype
IgG1
Clone Number
SJ25-C1
Host
Mouse
Species Reactivity
Human CD19
Form/Format
Liquid in PBS, pH 7.4
Concentration
0.5 mg/ml (lot specific)
Biological Significance
B-lymphocyte antigen CD19 also known as CD19 (Cluster of Differentiation 19), is a protein that in humans is encoded by the CD19 gene.
Immunogen
CD19 antibody (Azide free) was raised in mouse using human CD19 as the immunogen.
Preparation and Storage
Aliquot and store at -20 degree C. Avoid repeated freeze/thaw cycles
Other Notes
Small volumes of anti-CD19 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CD19 antibody
Mouse monoclonal CD19 antibody (Azide Free)
Product Categories/Family for anti-CD19 antibody
Applications Tested/Suitable for anti-CD19 antibody
Flow Cytometry (FC/FACS), Immunohistochemistry-Frozen (IHC-F), Immunoprecipitation (IP)
Application Notes for anti-CD19 antibody
Endotoxin Level: < = 6.25 EU/ml at 0.5mg/ml as determined by LAL.
NCBI/Uniprot data below describe general gene information for CD19. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
61,200 Da
NCBI Official Full Name
B-lymphocyte antigen CD19 isoform 2
NCBI Official Synonym Full Names
CD19 molecule
NCBI Official Symbol
NCBI Official Synonym Symbols
B4; CVID3
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NCBI Protein Information
B-lymphocyte antigen CD19
UniProt Protein Name
B-lymphocyte antigen CD19
UniProt Synonym Protein Names
B-lymphocyte surface antigen B4; Differentiation antigen CD19; T-cell surface antigen Leu-12; CD_antigen: CD19
Protein Family
UniProt Gene Name
UniProt Entry Name
CD19_HUMAN
NCBI Summary for CD19
Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. [provided by RefSeq, Jul 2008]
UniProt Comments for CD19
CD19: a cell surface molecule which assembles with the antigen receptor of B lymphocytes. A critical signal transduction molecule that regulates B lymphocyte development, activation, and differentiation. Ligation increases intracellular calcium levels and decreases the threshold for antigen receptor signaling. Germinal center formation is significantly reduced in CD19-deficient mice.

Protein type: Cell surface; Membrane protein, integral

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: protein complex; integral to plasma membrane; plasma membrane; external side of plasma membrane

Molecular Function: receptor signaling protein activity

Biological Process: epidermal growth factor receptor signaling pathway; B cell receptor signaling pathway; regulation of immune response; fibroblast growth factor receptor signaling pathway; phosphoinositide-mediated signaling; cell surface receptor linked signal transduction; nerve growth factor receptor signaling pathway; innate immune response; cellular defense response; positive regulation of release of sequestered calcium ion into cytosol

Disease: Immunodeficiency, Common Variable, 2; Immunodeficiency, Common Variable, 3
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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