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anti-CD30 antibody :: Mouse anti-Human CD30 Monoclonal Antibody

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Catalog # MBS245116
Unit / Price
  0.05 mg  /  $530 +1 FREE 8GB USB
Immunohistochemistry (IHC)
Product Name

CD30, Monoclonal Antibody

Also Known As

Mouse Monoclonal [clone MEM-268] (IgG) to Human CD30

Product Synonym Names
Anti-CD30 Antibody (clone MEM-268) IHC-plus; TNFRSF8; CD30L receptor; CD30; Cytokine receptor CD30; D1S166E; Ki-1; Ki-1 antigen; CD30 antigen; Human CD30
Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
595
OMIM
153243
3D Structure
ModBase 3D Structure for P28908
Clonality
Monoclonal
Isotype
IgG
Clone Number
MEM-268
Host
Mouse
Species Reactivity
Human
Specificity
Expression vector containing CD30 cDNA (booster suspension of THP-1 cell line)
Purity/Purification
Protein A Purified
Form/Format
PBS, 15 mM sodium azide, approx., pH 7.4.
Concentration
1 mg/ml (lot specific)
Target Species
Human
Immunogen Description
Cells.
Immunogen
CD30 antibody was raised against cells.
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
Other Notes
Small volumes of anti-CD30 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-CD30 antibody
Applications Tested/Suitable for anti-CD30 antibody
Immunohistochemistry (IHC - Paraffin), Flow Cytometry (FC/FACS)
Application Notes for anti-CD30 antibody
Flo, IHC-P (5 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-CD30 antibody
Anti-TNFRSF8 / CD30 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
anti-CD30 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for CD30. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
50,935 Da
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 8 isoform 1
NCBI Official Synonym Full Names
tumor necrosis factor receptor superfamily, member 8
NCBI Official Symbol
TNFRSF8  [Similar Products]
NCBI Official Synonym Symbols
CD30; Ki-1; D1S166E
  [Similar Products]
NCBI Protein Information
tumor necrosis factor receptor superfamily member 8; Ki-1 antigen; CD30L receptor; cytokine receptor CD30; lymphocyte activation antigen CD30
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 8
UniProt Synonym Protein Names
CD30L receptor; Ki-1 antigen; Lymphocyte activation antigen CD30; CD_antigen: CD30
Protein Family
UniProt Gene Name
TNFRSF8  [Similar Products]
UniProt Synonym Gene Names
CD30; D1S166E  [Similar Products]
UniProt Entry Name
TNR8_HUMAN
NCBI Summary for CD30
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
UniProt Comments for CD30
TNFRSF8: Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF- kappa-B. 2 isoforms of the human protein are produced by alternative initiation.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 1p36

Cellular Component: cytoplasm; integral to membrane; plasma membrane

Molecular Function: transmembrane receptor activity

Biological Process: negative regulation of cell proliferation; positive regulation of tumor necrosis factor biosynthetic process; positive regulation of apoptosis; positive regulation of TRAIL biosynthetic process; signal transduction
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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