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anti-CD83 antibody :: Mouse anti-Human CD83 Monoclonal Antibody

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Catalog # MBS530698
Unit / Price
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  120 Tests  /  $650 +1 FREE 8GB USB
anti-CD83 antibody
Product Name

CD83, Monoclonal Antibody

Full Product Name

CD83 antibody (PE)

Product Synonym Names
Monoclonal CD83; Anti-CD83; CD 83; CD-83; CD83
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
604534
3D Structure
ModBase 3D Structure for Q01151
Clonality
Monoclonal
Isotype
IgG1
Clone Number
HB15e
Host
Mouse
Species Reactivity
Human
Purity/Purification
CD83 antibody (PE) was purified by Protein A chromatography.
Form/Format
50mM Na3PO4, pH 7.5, with 500mM KCL, 150mM NaCl, 15% Glycerol, 0.2% BSA, and 0.04% NaN3.
Concentration
0.5 mg/ml (lot specific)
Biological Significance
Human CD83 is a type 1 cell surface glycoprotein expressed almost solely by dendritic cells that play an important role in antigen presentation.
Biohazard Information
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Tag/Conjugate
PE
Immunogen
CD83 antibody (PE) was raised in mouse using COS cells transfected with human CD83 as the immunogen.
Preparation and Storage
Store at 4 degree C. DO NOT FREEZE. Keep away from light.
Other Notes
Small volumes of anti-CD83 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CD83 antibody
Mouse monoclonal CD83 antibody (PE)
Applications Tested/Suitable for anti-CD83 antibody
Flow Cytometry (FC/FACS)
Application Notes for anti-CD83 antibody
FC: 20 ug/ml
NCBI/Uniprot data below describe general gene information for CD83. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
23,042 Da
NCBI Official Full Name
CD83 antigen isoform b
NCBI Official Synonym Full Names
CD83 molecule
NCBI Official Symbol
NCBI Official Synonym Symbols
BL11; HB15
  [Similar Products]
NCBI Protein Information
CD83 antigen
UniProt Protein Name
CD83 antigen
UniProt Synonym Protein Names
B-cell activation protein; Cell surface protein HB15; CD_antigen: CD83
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
hCD83  [Similar Products]
UniProt Entry Name
CD83_HUMAN
NCBI Summary for CD83
The protein encoded by this gene is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The encoded protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
UniProt Comments for CD83
CD83: May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 6p23

Cellular Component: integral to plasma membrane; plasma membrane; external side of plasma membrane

Biological Process: negative regulation of interleukin-4 production; positive regulation of interleukin-2 production; defense response; positive regulation of CD4-positive, alpha beta T cell differentiation; signal transduction; response to organic cyclic substance; positive regulation of interleukin-10 production; humoral immune response
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with anti-CD83 antibody
 Products by Pathway  Pathway Diagram
 TCR Signaling Pathway antibodies  TCR Signaling Pathway Diagram
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