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anti-CKB antibody :: Host: Mouse anti-Human Creatine Kinase BB (CK-BB) Monoclonal Antibody

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Catalog # MBS311596
Unit / Price
  1 mg  /  $320 +1 FREE 8GB USB
anti-CKB antibody
Product Name

Creatine Kinase BB (CK-BB) (CKB), Monoclonal Antibody

Popular Item
Also Known As

MAb to CK-BB

Product Synonym Names
Monoclonal Antibody to Human Creatine Kinase BB (CK-BB)
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
381
Chromosome Location
Chromosome: 14; NC_000014.8 (103985996..103989170, complement). Location: 14q32
OMIM
123280
3D Structure
ModBase 3D Structure for P12277
Clonality
Monoclonal
Isotype
IgG1, kappa
Clone Number
027-11288
Host
Host: Mouse
Species Reactivity
Human
Specificity
Creatine Kinase BB (CK-BB)
Human CK-BB
Purity/Purification
>90% pure (SDS-PAGE). Protein A chromatography
Product is 0.2um filtered.
Form/Format
Purified, Liquid
Concentration
4.92mg/ml (OD280nm, E^0.1% = 1.4) (lot specific)
Source
Ascites
Immunogen
Source: Human Brain
Affinity Constant
Not determined.
Buffer
10mM Phosphate, pH 7.4 containing 150mM Sodium Chloride
Preservative
0.05% Sodium Azide
Important Note
Centrifuge before opening to ensure complete recovery of vial contents.
Warnings
This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Preparation and Storage
Short term (up to 7 days) store at 2 to 8 degree C. Long term, aliquot and store at -20 degree C. If aliquoted for long term storage, fill volume should be equal to or greater than 50% of the nominal fill volume of the vial used. Avoid repeated freeze/thaw.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-CKB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Application Notes for anti-CKB antibody
Specific methodologies have not been tested using this product.
NCBI/Uniprot data below describe general gene information for CKB. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Creatine kinase B-type
NCBI Official Synonym Full Names
creatine kinase, brain
NCBI Official Symbol
NCBI Official Synonym Symbols
B-CK; CKBB
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NCBI Protein Information
creatine kinase B-type; creatine kinase-B; creatine kinase B chain
UniProt Protein Name
Creatine kinase B-type
UniProt Synonym Protein Names
B-CK; Creatine kinase B chain
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
UniProt Entry Name
KCRB_HUMAN
NCBI Summary for CKB
The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized. [provided by RefSeq]
UniProt Comments for CKB
Function: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.

Catalytic activity: ATP + creatine = ADP + phosphocreatine.

Subunit structure: Dimer of identical or non-identical chains. With MM being the major form in skeletal muscle and myocardium, MB existing in myocardium, and BB existing in many tissues, especially brain.

Subcellular location: Cytoplasm.

Sequence similarities: Belongs to the ATP:guanido phosphotransferase family.Contains 1 phosphagen kinase C-terminal domain.Contains 1 phosphagen kinase N-terminal domain.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withanti-CKB antibody
 Reference Product  PubMed Publications
 CKM antibody  >11 publications with CKB and CKM
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