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anti-CREST antibody :: Mouse anti-Human CREST Monoclonal Antibody

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Catalog # MBS768204
Unit / Price
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  0.1 mg  /  $320 +1 FREE 8GB USB
SDS-PAGE
Product Name

CREST, Monoclonal Antibody

Popular Item
Full Product Name

CREST Mouse Monoclonal

Product Synonym Names
CREST, KIAA0693, LP2261, SS18 like protein 1, SS18L1, SYT homolog 1
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS768204 Technical Datasheet
3D Structure
ModBase 3D Structure for O75177
Clonality
Monoclonal
Isotype
IgG1
Host
Mouse
Species Reactivity
Human
Specificity
Human, Mouse, Rat; other species are not tested. Please decide the specificity by homology
Purity/Purification
>=95% as determined by SDS-PAGE
Protein A+G purification
Form/Format
Liquid
Immunogen
Synovial sarcoma translocation gene on chromosome 18-like 1
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-CREST antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CREST antibody
Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity).
Applications Tested/Suitable for anti-CREST antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-CREST antibody
WB : 1:1000-1:6000

NIH/3T3 cells were subjected to SDS PAGE followed by western blot with MBS768204 (CREST antibody) at dilution of 1:3000
anti-CREST antibody SDS-PAGE image
NCBI/Uniprot data below describe general gene information for CREST. It may not necessarily be applicable to this product.
UniProt Primary Accession #
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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