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anti-CRNKL1 antibody :: Mouse anti-Human CRNKL1 Monoclonal Antibody

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Catalog # MBS120182
Unit / Price
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  0.1 mg  /  $395 +1 FREE 8GB USB
Product Name

CRNKL1, Monoclonal Antibody

Full Product Name

Mouse monoclonal antibody Anti-Human CRNKL1

Product Synonym Names
Homo sapiens Crn, crooked neck-like 1 (Drosophila) (CRNKL1), mRNA; CRN; HCRN; MSTP021
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
610952
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2212C1a
Host
Mouse
Species Reactivity
Human
Concentration
100 ug/ml (1.0 ml) (lot specific)
Preparation
This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Sterility
Filtered through a 0.22 um membrane.
Other Notes
Small volumes of anti-CRNKL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CRNKL1 antibody
The crooked neck (crn) gene of Drosophila is essential for embryogenesis and is thought to be involved in cell cycle progression and pre-mRNA splicing. This gene is similar in sequence to crn and encodes a protein which can localize to pre-mRNA splicing complexes in the nucleus. The encoded protein, which contains many tetratricopeptide repeats, is required for pre-mRNA splicing. [NCBI Entrez Gene Summary]
Applications Tested/Suitable for anti-CRNKL1 antibody
Dot Blot (DB), Immunocytochemistry (ICC)

Quality Control of anti-CRNKL1 antibody
Western blot analysis of immunized recombinant protein, using anti-CRNKL1 monoclonal antibody.
anti-CRNKL1 antibody Quality Control image
Quality Control #2 of anti-CRNKL1 antibody
Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.
anti-CRNKL1 antibody Quality Control #2 image
Immunocytochemistry (ICC) of anti-CRNKL1 antibody
Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-CRNKL1 mAb. [Lot No. 2212C1a-1]
anti-CRNKL1 antibody Immunocytochemistry (ICC) (ICC) image
NCBI/Uniprot data below describe general gene information for CRNKL1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
7,946 Da
NCBI Official Full Name
Homo sapiens crooked neck pre-mRNA splicing factor 1 (CRNKL1), transcript variant 1, mRNA
NCBI Official Synonym Full Names
crooked neck pre-mRNA splicing factor 1
NCBI Official Symbol
CRNKL1  [Similar Products]
NCBI Official Synonym Symbols
CLF; CRN; Clf1; HCRN; SYF3; MSTP021
  [Similar Products]
NCBI Protein Information
crooked neck-like protein 1; Crn, crooked neck-like 1; SYF3 pre-mRNA-splicing factor; crooked neck homolog; crooked neck pre-mRNA splicing factor-like 1
UniProt Protein Name
Crooked neck-like protein 1
UniProt Synonym Protein Names
Crooked neck homolog; hCrn
Protein Family
UniProt Gene Name
CRNKL1  [Similar Products]
UniProt Entry Name
CRNL1_HUMAN
NCBI Summary for CRNKL1
The crooked neck (crn) gene of Drosophila is essential for embryogenesis and is thought to be involved in cell cycle progression and pre-mRNA splicing. A protein encoded by this human locus has been found to localize to pre-mRNA splicing complexes in the nucleus and is necessary for pre-mRNA splicing. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2013]
UniProt Comments for CRNKL1
CRNKL1: Involved in pre-mRNA splicing process. Belongs to the crooked-neck family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Spliceosome; RNA processing; RNA splicing

Chromosomal Location of Human Ortholog: 20p11.2

Cellular Component: spliceosome; cytoplasm; nuclear speck

Molecular Function: protein binding; RNA binding

Biological Process: nuclear mRNA splicing, via spliceosome; spliceosome assembly
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Diseases associated with anti-CRNKL1 antibody
 Disease Name  Pubmed Publications
 Aneuploidy Antibodies  >1 publications with CRNKL1 and Aneuploidy
Organs/Tissues associated with anti-CRNKL1 antibody
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >1 publications with CRNKL1 and Skin
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