View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List anti-CCNA1 antibody :: Mouse anti-Human Cyclin A1/CCNA1 Monoclonal Antibody Catalog # MBS2543544 Unit / Price 0.06 mL / $260 +1 FREE 8GB USB 0.12 mL / $380 +1 FREE 8GB USB 0.2 mL / $560 +1 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Cyclin A1/CCNA1, Monoclonal Antibody Popular Item Full Product Name Mouse anti Human Cyclin A1/CCNA1 Monoclonal Antibody Product Gene Name anti-CCNA1 antibody[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP OMIM U66838 mRNA Clonality Monoclonal Isotype IgG2b Host Mouse Species Reactivity Human Immunogen Recombinant Human Cyclin A1/CCNA1 protein Buffer 0.2 mum filtered solution in PBS with 5% trehalose Preparation and Storage This antibody can be stored at 2 degree C- 8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. ISO Certification Manufactured in an ISO 9001:2015 Certified Laboratory. Other Notes Small volumes of anti-CCNA1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Applications Tested/Suitable for anti-CCNA1 antibody Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cyometry (FC/FACS) Application Notes for anti-CCNA1 antibody Flow Cytometry: 0.5-2 mug/TestICC/IF: 10-25 mug/mL TOP NCBI/Uniprot data below describe general gene information for CCNA1. It may not necessarily be applicable to this product. NCBI GI # 23271353 NCBI GeneID 8900 UniProt Secondary Accession # Q5T3V0; Q5U0G2; Q8IY91; B7Z7E3[Other Products] UniProt Related Accession # P78396[Other Products] Molecular Weight 47,494 Da TOP NCBI Official Full Name Cyclin A1 NCBI Official Synonym Full Names cyclin A1 NCBI Official Symbol CCNA1 [Similar Products] NCBI Official Synonym Symbols CT146 [Similar Products] NCBI Protein Information cyclin-A1 UniProt Protein Name Cyclin-A1 Protein Family Cyclin UniProt Gene Name CCNA1 [Similar Products] UniProt Entry Name CCNA1_HUMAN TOP NCBI Summary for CCNA1 The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. This cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] TOP UniProt Comments for CCNA1 CCNA1: May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells. Belongs to the cyclin family. Cyclin AB subfamily. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Cancer Testis Antigen (CTA); Cell cycle regulation; Nuclear receptor co-regulatorChromosomal Location of Human Ortholog: 13q12.3-q13Cellular Component: cytosol; microtubule cytoskeleton; nucleoplasmMolecular Function: protein bindingBiological Process: G1/S transition of mitotic cell cycle; G1/S-specific transcription in mitotic cell cycle; male meiosis I; spermatogenesis Research Articles on CCNA1 1. The data showed that E7 induced CCNA1 methylation by forming a complex with Dnmt1 at the CCNA1 promoter, resulting in the subsequent reduction of expression in cancers. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with anti-CCNA1 antibody Reference Product PubMed Publications CDK2 antibody >22 publications with CCNA1 and CDK2 CCNB1 antibody >16 publications with CCNA1 and CCNB1 CDKN1A antibody >12 publications with CCNA1 and CDKN1A CDK1 antibody >7 publications with CCNA1 and CDK1 CDKN1B antibody >6 publications with CCNA1 and CDKN1B E2F1 antibody >3 publications with CCNA1 and E2F1 RB1 antibody >2 publications with CCNA1 and RB1 CDC25A antibody >2 publications with CCNA1 and CDC25A Pathways associated with anti-CCNA1 antibody Products by Pathway Pathway Diagram AMP-activated Protein Kinase (AMPK) Signaling Pathway antibodies AMP-activated Protein Kinase (AMPK) Signaling Pathway Diagram AMPK Signaling Pathway antibodies AMPK Signaling Pathway Diagram AMPK Signaling Pathway antibodies AMPK Signaling Pathway Diagram APC/C-mediated Degradation Of Cell Cycle Proteins Pathway antibodies APC/C-mediated Degradation Of Cell Cycle Proteins Pathway Diagram APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway antibodies APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway Diagram APC:Cdc20 Mediated Degradation Of Cell Cycle Proteins Prior To Satisfation Of The Cell Cycle Checkpoint Pathway antibodies APC:Cdc20 Mediated Degradation Of Cell Cycle Proteins Prior To Satisfation Of The Cell Cycle Checkpoint Pathway Diagram Activation Of APC/C And APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway antibodies Activation Of APC/C And APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway Diagram Acute Myeloid Leukemia Pathway antibodies Acute Myeloid Leukemia Pathway Diagram Acute Myeloid Leukemia Pathway antibodies Acute Myeloid Leukemia Pathway Diagram C-MYB Transcription Factor Network Pathway antibodies C-MYB Transcription Factor Network Pathway Diagram Diseases associated with anti-CCNA1 antibody Disease Name Pubmed Publications Breast Neoplasms Antibodies >14 publications with CCNA1 and Breast Neoplasms Neoplasms, Experimental Antibodies >13 publications with CCNA1 and Neoplasms, Experimental Cell Transformation, Neoplastic Antibodies >11 publications with CCNA1 and Cell Transformation, Neoplastic Infertility, Male Antibodies >8 publications with CCNA1 and Infertility, Male Lung Neoplasms Antibodies >8 publications with CCNA1 and Lung Neoplasms Papillomavirus Infections Antibodies >6 publications with CCNA1 and Papillomavirus Infections Lung Diseases Antibodies >6 publications with CCNA1 and Lung Diseases Nervous System Diseases Antibodies >4 publications with CCNA1 and Nervous System Diseases Cardiovascular Diseases Antibodies >4 publications with CCNA1 and Cardiovascular Diseases Carcinoma, squamous cell of head and neck Antibodies >4 publications with CCNA1 and Carcinoma, squamous cell of head and neck Organs/Tissues associated with anti-CCNA1 antibody Organ/Tissue Name Pubmed Publications Testis Antibodies >23 publications with CCNA1 and Testis Lung Antibodies >12 publications with CCNA1 and Lung Bone Marrow Antibodies >8 publications with CCNA1 and Bone Marrow Vascular Antibodies >6 publications with CCNA1 and Vascular Cervix Antibodies >6 publications with CCNA1 and Cervix Brain Antibodies >6 publications with CCNA1 and Brain Kidney Antibodies >5 publications with CCNA1 and Kidney Nerve Antibodies >5 publications with CCNA1 and Nerve Eye Antibodies >4 publications with CCNA1 and Eye Pancreas Antibodies >3 publications with CCNA1 and Pancreas TOP