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D-dimer mAb (Mouse anti-human, clone # D10)-Detection Ab Monoclonal Antibody

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Catalog # MBS355010
Unit / Price
  1 mg  /  $420 +1 FREE 8GB USB
anti-D-dimer mAb (Mouse anti-human, clone # D10)-Detection Ab antibody
Product Name

D-dimer mAb (Mouse anti-human, clone # D10)-Detection Ab, Monoclonal Antibody

Popular Item
Also Known As

D-dimer (Detection Ab)

Product Synonym Names
Monoclonal Anti- D-dimer (Detection Ab)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
D10
Host
Mouse
Species Reactivity
Human
Specificity
It specifically recognize human D-dimer antigen, and does not cross react with BSA, but has week cross-reactivity with fibrinogen.
Purity/Purification
Protein A or G purified and supplied in 0.01 M PBS (pH7.4) without preservative.
>95% by HPLC & SDS-PAGE
Form/Format
Liquid
Concentration
3 mg/ml (lot specific)
Immunogen
Human D-dimer protein.
Matched Antibody Pairs
Capture Ab: D-dimer mAb (clone # C6) or D-dimer mAb (clone # C9)
Detection Ab: D-dimer mAb (clone # D10)
Preparation and Storage
Aliquot and store at -20 degree C for long term (at least one year). Avoid repeated freeze and thaw cycles.
Other Notes
Small volumes of anti-D-dimer mAb (Mouse anti-human, clone # D10)-Detection Ab antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
D-dimer is a fibrin degradation product (or FDP), a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis. It is so named because it contains two crosslinked D fragments of the fibrin protein. The D-dimer antigen is a unique marker of fibrin degradation that is formed by the sequential action of 3 enzymes: thrombin, factor XIIIa, and plasmin. Its concentration may be determined by a blood test to help diagnose thrombosis. Since its introduction in the 1990s, it has become an important test performed in patients suspected of thrombotic disorders. While a negative result practically rules out thrombosis, a positive result can indicate thrombosis but does not rule out other potential causes. Its main use, therefore, is to exclude thromboembolic disease where the probability is low. In addition, it is used in the diagnosis of the blood disorder disseminated intravascular coagulation.
Western Blot (WB), Lateral Flow (LF), ELISA (EIA)
WB, ELISA, Lateral flow assay (rapid test)
1. Adam SS, Key NS, Greenberg CS (March 2009). "D-dimer antigen: current concepts and future prospects". Blood 113 (13): 2878-2887.

Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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