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anti-lasB antibody :: Mouse Elastase Monoclonal Antibody

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Catalog # MBS530049
Unit / Price
  0.5 mg  /  $385 +1 FREE 8GB USB
anti-lasB antibody
Product Name

Elastase (lasB), Monoclonal Antibody

Popular Item
Full Product Name

Elastase antibody

Product Synonym Names
Monoclonal Elastase; Anti-Elastase
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Clonality
Monoclonal
Isotype
IgG1
Clone Number
M2110125
Host
Mouse
Species Reactivity
Human elastase
Form/Format
Supplied in PBS buffer with no preservatives added.
Biological Significance
Elastase breaks down elastin, an elastic fiber that, together with collagen, determines the mechanical properties of connective tissue. The neutrophil form breaks down the Outer membrane protein A (OmpA) of E Coli and other Gram-negative bacteria. Elastase also has the important immunological role of breaking down Shigella virulence factors.
Immunogen
Elastase antibody was raised in mouse using purified human neutrophil elastase as the immunogen.
Preparation and Storage
Aliquot and store at -70 degree C or lower. Avoid repeated freeze/thaw cycles
Other Notes
Small volumes of anti-lasB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-lasB antibody
Mouse monoclonal Elastase antibody
Applications Tested/Suitable for anti-lasB antibody
ELISA (EIA)
Application Notes for anti-lasB antibody
ELISA: 1:51,200
NCBI/Uniprot data below describe general gene information for lasB. It may not necessarily be applicable to this product.
NCBI GI #
NCBI Accession #
Molecular Weight
53,687 Da[Similar Products]
NCBI Official Full Name
elastase (EC 3.4.24.4)
UniProt Protein Name
Elastase
UniProt Synonym Protein Names
Neutral metalloproteinase; PAE
Protein Family
UniProt Gene Name
UniProt Entry Name
ELAS_PSEAE
UniProt Comments for lasB
Cleaves host elastin, collagen, IgG, and several complement components as well as endogenous pro-aminopeptidase (PubMed:11533066). Autocatalyses processing of its pro-peptide (PubMed:9642203, PubMed:1744034). Processes the pro-peptide of pro-chitin-binding protein (cbpD) (PubMed:9642203). Involved in the pathogenesis of P.aeruginosa infections.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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