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anti-Fabp3 antibody :: Mouse anti-Human Fatty Acid Binding Protein, Heart Monoclonal Antibody

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Catalog # MBS602230
Unit / Price
  0.1 mg  /  $745 +1 FREE 8GB USB
anti-Fabp3 antibody
Product Name

Fatty Acid Binding Protein, Heart (Fabp3), Monoclonal Antibody

Also Known As

Fatty Acid Binding Protein, Heart (FABP)

Product Synonym Names
Anti -Fatty Acid Binding Protein, Heart (FABP)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 5; NC_005104.2 (149340525..149347268). Location: 5q36
3D Structure
ModBase 3D Structure for P07483
Clonality
Monoclonal
Isotype
IgG1
Clone Number
3H429
Host
Mouse
Species Reactivity
Human
Specificity
Recognizes human heart FABP. Isoform crossreactivity
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.4 and 0.1% sodium azide, 40% glycerol.
Immunogen
Purified human heart FABP (> 98%).
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Other Notes
Small volumes of anti-Fabp3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-Fabp3 antibody
Fatty acids are important for general cellular metabolism. A number of proteins have been implicated in the transport and storage of fatty acid. FABPs (fatty acid binding proteins) are a group of cytoplasmic, small mol wt (14-15kD) and proteins that has widespread tissue distribution. FABPs are quite abundant (3-5% of total cellular protein). At least 7 FABPs, FABP1-7, have been cloned and characterized from various tissues. FABPs can bind long-chain fatty acid, fatty-acid acyl-CoA and acyl-L-carnitine. Several different isoform of FABP have been identified and generally referred to by tissue type (liver, heart, intestine, adipocyte, kidney, brain etc; protein designated as H-FABP indicates that it is heart type). However, expression of these isoform is not exclusive and more than one isoform can be found in aH given cell or tissue. Three main types of FABPs that were initially discovered in the heart (FABP-), liver (FABP-L), and intestine (FABP-I) are not exclusive these tissues and show considerable differences at the amino acid level (~30% identity). Other FABPs recently detected in adipocyte, kidney, and brain show a high degree of sequence homology among each other and with other FABPs. FABPs are also known as mammary derived growth inhibitor (MDGI), adipocyte lipid binding protein (ALBP), Myelin protein P2 homolog, P2 adipocyte protein, 422 protein (P15). Human FABP-H or adipocyte is 132-aa protein (chromosome 2p11) Rat and mouse adipocyte-FABPs are 133 aa single polypeptide chains.
Applications Tested/Suitable for anti-Fabp3 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-Fabp3 antibody
Suitable for use in Western Blot and ELISA.
Dilution: Western Blot: 1:1000-1:5000. Use +ve as control (refer to Catalog F0019-77M). Load ~10ul/lane.
ELISA: 1:10,000-1:50,000.
NCBI/Uniprot data below describe general gene information for Fabp3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
14,775 Da[Similar Products]
NCBI Official Full Name
fatty acid-binding protein, heart
NCBI Official Synonym Full Names
fatty acid binding protein 3, muscle and heart
NCBI Official Symbol
Fabp3  [Similar Products]
NCBI Official Synonym Symbols
Fabp3
  [Similar Products]
NCBI Protein Information
fatty acid-binding protein, heart; H-FABP; fatty acid-binding protein 3; heart fatty acid binding protein; Fatty acid binding protein 3 heart; fatty acid binding protein 3 heart; heart-type fatty acid-binding protein
UniProt Protein Name
Fatty acid-binding protein, heart
UniProt Synonym Protein Names
Fatty acid-binding protein 3; Heart-type fatty acid-binding protein
UniProt Gene Name
Fabp3  [Similar Products]
UniProt Entry Name
FABPH_RAT
NCBI Summary for Fabp3
binds fatty acids; may play a role in fatty acid metabolism possibly including mitochondrial beta-oxidation of fatty acids [RGD]
UniProt Comments for Fabp3
FABP3: FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Protein type: Lipid-binding

Cellular Component: extracellular space; mitochondrion; sarcoplasmic reticulum; cytoplasm; cytosol; sarcoplasm

Molecular Function: icosatetraenoic acid binding; cytoskeletal protein binding; long-chain fatty acid transporter activity; fatty acid binding

Biological Process: response to drug; long-chain fatty acid transport; cholesterol homeostasis; fatty acid beta-oxidation; regulation of fatty acid oxidation; fatty acid metabolic process; response to insulin stimulus; phospholipid homeostasis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with anti-Fabp3 antibody
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