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anti-FCGR2A antibody :: Mouse anti-Human FCGR2A Monoclonal Antibody

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Catalog # MBS533875
Unit / Price
  0.1 mL  /  $515 +1 FREE 8GB USB
Product Name

FCGR2A, Monoclonal Antibody

Popular Item
Also Known As

FCGR2A antibody

Product Synonym Names
Monoclonal FCGR2A; Anti-FCGR2A; Fc fragment of IgG low affinity IIa receptor CD32; CD32; IGFR2; CDw32; CD32A; Fc-gamma RII-a; IgG Fc receptor IIa; FCG2; FCGR2A1; CD32 antigen; FCGR2A; FCGRA 2; FCGRA-2
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
316
OMIM
146790
3D Structure
ModBase 3D Structure for P12318
Clonality
Monoclonal
Isotype
IgG1
Clone Number
15G5
Host
Mouse
Species Reactivity
Human
Purity/Purification
FCGR2A antibody was purified by affinity chromatography.
Form/Format
Purified liquid from ascites in PBS, pH 7.3, with 1% BSA, 50% glycerol, and 0.02% sodium azide.
Concentration
0.77mg/ml (lot specific)
Biological Significance
FCGR2A is a member of a family of immunoglobulin Fc receptor genes found on the surface of many immuneresponse cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such asmacrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes.
Immunogen
Full length human recombinant protein of human FCGR2A produced in HEK293T cell
Additional Remarks
Suitable for use in WB (1/200- 1/1000), IHC (1/50), IF (1/100), IP (2ug/500ul)
Preparation and Storage
Ships at 4 degee C only. Upon receipt store at -20 degree C. Dilute in PBS, pH 7.3, if necessary. Avoid repeat freeze/thaw cycles.
Other Notes
Small volumes of anti-FCGR2A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-FCGR2A antibody
Mouse monoclonal FCGR2A antibody
Product Categories/Family for anti-FCGR2A antibody
Applications Tested/Suitable for anti-FCGR2A antibody
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-FCGR2A antibody
IF: 1:100
IHC: 1:50
WB: 1:1000

Western Blot (WB) of anti-FCGR2A antibody
Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant FCGR2A protein (Right) or empty vector (Left) detected with FCGR2A antibody
anti-FCGR2A antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-FCGR2A antibody
Immunohistochemical analysis of FCGR2A protein in paraffin embedded Human endometrium tissue using FCGR2A antibody
anti-FCGR2A antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for FCGR2A. It may not necessarily be applicable to this product.
NCBI GI #
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
Molecular Weight
34,930 Da
UniProt Protein Name
Low affinity immunoglobulin gamma Fc region receptor II-a
UniProt Synonym Protein Names
CDw32; Fc-gamma RII-a; Fc-gamma-RIIa; FcRII-a; CD_antigen: CD32
UniProt Gene Name
FCGR2A  [Similar Products]
UniProt Synonym Gene Names
CD32; FCG2; FCGR2A1; IGFR2; IgG Fc receptor II-a; Fc-gamma-RIIa; FcRII-a  [Similar Products]
UniProt Entry Name
FCG2A_HUMAN
UniProt Comments for FCGR2A
FCGR2A: low affinity receptor for the Fc region of IgGs. Binding to IgG initiates cellular responses against pathogens and soluble antigens. A type I membrane protein found on monocytes, neutrophils and platelets. SHP-1 associates with this protein to modulate signaling events in myeloid cells.

Protein type: Cell surface; Receptor, misc.; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q23

Cellular Component: integral to membrane; plasma membrane

Molecular Function: IgG binding

Biological Process: innate immune response

Disease: Systemic Lupus Erythematosus; Malaria, Susceptibility To
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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