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anti-KAT5 antibody :: Mouse anti-Human HIV-1 Tat Interacting Protein, 60kD Monoclonal Antibody

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Catalog # MBS601906
Unit / Price
  0.1 mg  /  $565 +1 FREE 8GB USB
anti-KAT5 antibody
Product Name

HIV-1 Tat Interacting Protein, 60kD (KAT5), Monoclonal Antibody

Also Known As

HIV-1 Tat Interacting Protein, 60kD (HTATIP, HTATIP1, cPLA2-interacting Protein, ESA1, PLIP, TIP60)

Product Synonym Names
Anti -HIV-1 Tat Interacting Protein, 60kD (HTATIP, HTATIP1, cPLA2-interacting Protein, ESA1, PLIP, TIP60)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 11; NC_000011.9 (65479489..65487075). Location: 11q13
OMIM
601409
3D Structure
ModBase 3D Structure for Q92993
Clonality
Monoclonal
Isotype
IgG1
Clone Number
8C182
Host
Mouse
Species Reactivity
Human
Specificity
Recognizes human HIV-1 Tat Interacting Protein at ~60kD.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Form/Format
Supplied as a sterile-filtered liquid in PBS, pH 7.4, 1% BSA, 0.05% sodium azide.
Immunogen
Partial sequence from the internal region of recombinant full-length protein to human HIV-1 Tat Interacting Protein, 60kD
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Other Notes
Small volumes of anti-KAT5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-KAT5 antibody
Western Blot (WB), Immunocytochemistry (ICC)
Application Notes for anti-KAT5 antibody
Suitable for use in Western Blot and Immunocytochemistry.
NCBI/Uniprot data below describe general gene information for KAT5. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
58,582 Da[Similar Products]
NCBI Official Full Name
HIV-1 Tat interacting protein, 60kDa, isoform CRA_c
NCBI Official Synonym Full Names
K(lysine) acetyltransferase 5
NCBI Official Symbol
NCBI Official Synonym Symbols
TIP; ESA1; PLIP; TIP60; cPLA2; HTATIP; HTATIP1
  [Similar Products]
NCBI Protein Information
histone acetyltransferase KAT5; OTTHUMP00000233811; OTTHUMP00000233812; OTTHUMP00000233813; OTTHUMP00000233848; K-acetyltransferase 5; cPLA2 interacting protein; lysine acetyltransferase 5; cPLA(2)-interacting protein; 60 kDa Tat-interactive protein; Tat interacting protein, 60kDa; histone acetyltransferase HTATIP; HIV-1 Tat interactive protein, 60kDa
UniProt Protein Name
Histone acetyltransferase KAT5
UniProt Synonym Protein Names
60 kDa Tat-interactive protein; Tip60; Histone acetyltransferase HTATIP; HIV-1 Tat interactive protein; Lysine acetyltransferase 5; cPLA(2)-interacting protein
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
HTATIP; TIP60  [Similar Products]
UniProt Entry Name
KAT5_HUMAN
NCBI Summary for KAT5
The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq]
UniProt Comments for KAT5
Tip60: a histone acetyl transferase (HAT) of the MYST family. Originally isolated as an HIV-1 TAT-interactive protein. Plays an important role in regulating chromatin remodeling, transcription and other nuclear processes by acetylating nuclear proteins. Plays a role in DNA repair and apoptosis. Three splice variants have been described.

Protein type: Nucleolus; EC 2.3.1.48; Nuclear receptor co-regulator; Acetyltransferase

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: nucleoplasm; transcription factor complex; NuA4 histone acetyltransferase complex; perinuclear region of cytoplasm; nucleolus; nucleus; cytosol

Molecular Function: protein binding; histone acetyltransferase activity; androgen receptor binding; metal ion binding; transcription coactivator activity; protein complex binding

Biological Process: proteasomal ubiquitin-dependent protein catabolic process; establishment and/or maintenance of chromatin architecture; transcription, DNA-dependent; viral reproduction; positive regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; negative regulation of interleukin-2 production; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; double-strand break repair; regulation of growth; androgen receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; response to ionizing radiation; histone acetylation; negative regulation of transcription, DNA-dependent
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withanti-KAT5 antibody
 Reference Product  PubMed Publications
 CD82 antibody  >1 publications with KAT5 and CD82
Organs/Tissues associated with anti-KAT5 antibody
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