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anti-HNRPLL antibody :: Mouse anti-Human HNRPLL Monoclonal Antibody

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Catalog # MBS120513
Unit / Price
  0.1 mg  /  $345 +1 FREE 8GB USB
Product Name

HNRPLL, Monoclonal Antibody

Also Known As

Mouse monoclonal antibody Anti-Human HNRPLL

Product Synonym Names
Homo sapiens heterogeneous nuclear ribonucleoprotein L-like(HNRPLL), mRNA.; SRRF
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
3053
OMIM
611208
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
2432C3a
Host
Mouse
Species Reactivity
Human
Concentration
100 ug/ml (1.0 ml) (lot specific)
Preparation
This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Sterility
Filtered through a 0.22 um membrane.
Other Notes
Small volumes of anti-HNRPLL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-HNRPLL antibody
HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]).[supplied by OMIM][NCBI Entrez Gene Summary]
Applications Tested/Suitable for anti-HNRPLL antibody
Dot Blot (DB)

Quality Control of anti-HNRPLL antibody
Western blot analysis of immunized recombinant protein, using anti-HNRPLL monoclonal antibody.
anti-HNRPLL antibody Quality Control image
Quality Control #2 of anti-HNRPLL antibody
Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.
anti-HNRPLL antibody Quality Control #2 image
NCBI/Uniprot data below describe general gene information for HNRPLL. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
56,467 Da
NCBI Official Full Name
Homo sapiens heterogeneous nuclear ribonucleoprotein L-like (HNRNPLL), transcript variant 1, mRNA
NCBI Official Synonym Full Names
heterogeneous nuclear ribonucleoprotein L-like
NCBI Official Symbol
HNRNPLL  [Similar Products]
NCBI Official Synonym Symbols
SRRF; HNRPLL
  [Similar Products]
NCBI Protein Information
heterogeneous nuclear ribonucleoprotein L-like; stromal RNA regulating factor; stromal RNA-regulating factor
UniProt Protein Name
Heterogeneous nuclear ribonucleoprotein L-like
UniProt Synonym Protein Names
Stromal RNA-regulating factor
UniProt Gene Name
HNRNPLL  [Similar Products]
UniProt Entry Name
HNRLL_HUMAN
NCBI Summary for HNRPLL
HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]).[supplied by OMIM, Aug 2008]
UniProt Comments for HNRPLL
HNRPLL: RNA-binding protein that functions as regulator of alternative splicing for multiple target mRNAs, including PTPRC/CD45 and STAT5A. Required for alternative splicing of PTPRC. Interacts with HNRNPL. Up-regulated in stimulated T-cells. Widely expressed. Detected in bone marrow stroma cells, skeletal muscle, heart, placenta, pancreas, kidney and lung. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding

Chromosomal Location of Human Ortholog: 2p22.1

Cellular Component: membrane; nucleus; ribonucleoprotein complex

Molecular Function: mRNA binding; protein binding; nucleotide binding

Biological Process: mRNA processing; positive regulation of RNA splicing
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withanti-HNRPLL antibody
 Reference Product  PubMed Publications
 PTPRC antibody  >6 publications with HNRPLL and PTPRC
Organs/Tissues associated with anti-HNRPLL antibody
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