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anti-IFN-gamma antibody :: Mouse IFN-gamma Monoclonal Antibody

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Catalog # MBS592270
Unit / Price
  0.5 mg  /  $490 +1 FREE 8GB USB
anti-IFN-gamma antibody
Product Name

IFN-gamma, Monoclonal Antibody

Also Known As

mAb anti-Human IFN-gamma

Product Synonym Names
Interferon Gamma (IFN-gamma); Interferon Gamma (IFN-g); Mouse monoclonal antibody to human Interferon-gamma (IFN-gamma)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
166
OMIM
147570
Clonality
Monoclonal
Isotype
IgG1, k
Clone Number
23
Host
Mouse
Species Reactivity
Human. Other species not tested
Specificity
This antibody recognizes both recombinant and native human IFN-gamma.
Interferon Gamma (IFN-gamma)
Purity/Purification
Protein G affinity purified
Form/Format
Lyophilized from a solution in 0.01M PBS, pH 7.0
Target Protein
Human IFN-gamma
Immunogen
Purified recombinant human IFN-gamma
Myeloma
Sp2/0-Ag14
Light Chain
Kappa
Reconstitution
Double distilled water is recommended to adjust the final concentration to 1.00mg/mL.
Research Area
Pro-inflammatory cytokine, anti-tumour and anti-viral immunity
Preparation and Storage
Store at -20 degree C
Other Notes
Small volumes of anti-IFN-gamma antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-IFN-gamma antibody
Mouse monoclonal antibody to human Interferon-gamma (IFN-γ (gamma)), Protein G affinity purified
Applications Tested/Suitable for anti-IFN-gamma antibody
ELISA (EIA)
Application Notes for anti-IFN-gamma antibody
ELISA: The antibody reacts with recombinant IFN-gamma coated plate at 0.1ng/mL of antibody concentration
NCBI/Uniprot data below describe general gene information for IFN-gamma. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
19,348 Da
NCBI Official Full Name
interferon gamma
NCBI Official Synonym Full Names
interferon, gamma
NCBI Official Symbol
NCBI Official Synonym Symbols
IFG; IFI
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NCBI Protein Information
interferon gamma; IFN-gamma; immune interferon
UniProt Protein Name
Interferon gamma
UniProt Synonym Protein Names
Immune interferon
UniProt Gene Name
UniProt Entry Name
IFNG_HUMAN
NCBI Summary for IFN-gamma
This gene encodes a member of the type II interferon family. The protein encoded is a soluble cytokine with antiviral, immunoregulatory and anti-tumor properties and is a potent activator of macrophages. Mutations in this gene are associated with aplastic anemia.[provided by RefSeq, Nov 2009]
UniProt Comments for IFN-gamma
IFNG: Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. Homodimer. Released primarily from activated T lymphocytes. Belongs to the type II (or gamma) interferon family.

Protein type: Cytokine; Secreted; Secreted, signal peptide; Membrane protein, integral

Chromosomal Location of Human Ortholog: 12q14

Cellular Component: extracellular space; extracellular region; external side of plasma membrane

Molecular Function: interferon-gamma receptor binding; cytokine activity

Biological Process: positive regulation of isotype switching to IgG isotypes; positive regulation of nitric oxide biosynthetic process; positive regulation of osteoclast differentiation; apoptosis; positive regulation of interleukin-23 production; negative regulation of smooth muscle cell proliferation; positive regulation of interleukin-12 production; positive regulation of interleukin-6 biosynthetic process; negative regulation of epithelial cell differentiation; positive regulation of killing of cells of another organism; sensory perception of mechanical stimulus; positive regulation of interleukin-1 beta secretion; negative regulation of transcription from RNA polymerase II promoter; positive regulation of membrane protein ectodomain proteolysis; cell surface receptor linked signal transduction; positive regulation of MHC class II biosynthetic process; positive regulation of cell proliferation; positive regulation of mesenchymal cell proliferation; positive regulation of T cell proliferation; cell cycle arrest; defense response to virus; regulation of the force of heart contraction; positive regulation of peptidyl-serine phosphorylation of STAT protein; response to drug; positive regulation of synaptic transmission, cholinergic; neutrophil chemotaxis; adaptive immune response; CD8-positive, alpha-beta T cell differentiation during immune response; negative regulation of myelination; unfolded protein response; cytokine and chemokine mediated signaling pathway; response to virus; defense response to protozoan; positive regulation of tumor necrosis factor production; humoral immune response; antigen processing and presentation; positive regulation of tyrosine phosphorylation of Stat1 protein; negative regulation of interleukin-17 production; positive regulation of interleukin-12 biosynthetic process; positive regulation of chemokine biosynthetic process; protein import into nucleus, translocation; defense response to bacterium; neutrophil apoptosis; positive regulation of transcription from RNA polymerase II promoter; cell motility; positive regulation of neuron differentiation; regulation of insulin secretion

Disease: Hepatitis C Virus, Susceptibility To; Aplastic Anemia; Tuberous Sclerosis 2; Mycobacterium Tuberculosis, Susceptibility To; Human Immunodeficiency Virus Type 1, Susceptibility To
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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